Category: Research Publications

Prior exposure to childhood maltreatment contributes to changes in white matter microstructure of connections involved in carrying sensory information. Importantly, the effect of maltreatment on these connections is related to presence of PTSD symptoms up to 6-months after a traumatic event. These data highlight an important neural marker of later...

Childhood adversities (CAs) have been shown to predict increased risk of posttraumatic stress disorder (PTSD) and major depressive episode (MDE) among people exposed to adult traumatic events. Utilizing data from the AURORA study, Ziobrowski et al., examined whether patient-reported CAs (physical abuse, sexual abuse, emotional abuse, physical neglect, emotional neglect,...

Investigators assessed the course of adverse posttraumatic neuropsychiatric sequela symptoms (pain, depression, sleep, nightmares, avoidance, re-experiencing, anxiety, hyperarousal, somatic, and mental/fatigue symptoms) in over two thousand patients from the AURORA study over a two month period after a car accident The study found that APNS symptoms were common during the...

Within the AURORA study, participants of different racial/ethnic groups experience different levels of adversity and come from different socioeconomic backgrounds. As a result, these groups differ in basal levels of arousal both behaviorally and neurally which is then related to how MRI biomarkers predict future PTSD symptoms. These results are...

Peer mentorship is an important tool to promote faculty success, especially for individuals who engage in (typically undervalued) work to advance gender equity. The purpose of this research letter is to share our experiences establishing a “Gender Equity Works-in-Progress Group.”

Prenatal sleep disturbance as measured by a single-item administered in all three trimesters of pregnancy was associated with higher odds of postpartum depressive symptoms. A routinely administered single-item measure of sleep disturbance could identify otherwise lower-risk pregnant individuals who may benefit from depression prevention efforts.

This study looked at the proportion of men and women applicants and grant reviewers before and during the pandemic collected from the Health Research Alliance (HRA), which funds biomedical research and training. The gender composition of grant applicants and grant review panels remained similar, except for the review panel composition...

This publication provides an overview of a new clinical trial examining the effects of hormone replacement therapy on perimenopausal mood symptoms and brain indices of dopamine signaling.

A case series providing evidence that the impact of tACS is dependent on context of affective and brain state.

We propose that the best chance to discover biomarkers and treatment targets for psychiatric illness is to investigate the relationship between a specific symptom, the correlated mental activity, and the correlated neural activity signature.