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Longitudinal Analysis of Patient-Reported Cognitive Function in Multiple Myeloma

October 12, 2022
This is the first study describing longitudinal changes in patient-reported cognition in patients with multiple myeloma. Several potentially intervenable factors, including physical function impairment and depression, were associated with worse cognition at study entry, but only baseline cognitive impairment and education level were predictive of future cognitive decline.

The longitudinal effects of stress and fear on psychiatric symptoms in mothers during the COVID-19 pandemic

October 12, 2022
We surveyed mothers with a history of perinatal depression from June 2020 to January 2022 to assess their depressive and anxious symptoms throughout the COVID-19 pandemic. We found that local COVID-19 case rates and pandemic restrictions were not associated with symptoms, but prior severe perinatal depression, high stress, and feeling...

A Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder–Associated Impairment in Early Childhood

October 12, 2022
Males have historically been diagnosed with autism more frequently than females, with an approximately 4:1 ratio. This is the first evidence that, when using an unbiased data-driven method that accounts for potential sex-biases in measurement, the male to female sex ratio of may be more evenly distributed.

Predator odor (TMT) exposure potentiates interoceptive sensitivity to alcohol and increases GABAergic gene expression in the anterior insular cortex and nucleus accumbens in male rats

October 12, 2022
This study found that exposure to a stressor two weeks earlier potentiates the interoceptive/subjective effects of alcohol. This change may be relevant for understanding increased drinking following stress.

Socially Distanced Emergencies: Clinicians’ Experience with Tele-behavioral Health Safety Planning

October 12, 2022
This study examined clinicians’ experience in managing patient emergencies during virtual encounters, reinforcing the need for appropriate training regarding best practices while providing tele-behavioral health care.

Effects of varenicline and bupropion on laboratory smoking outcomes: Meta-analysis of randomized, placebo-controlled human laboratory studies

September 12, 2022
New study quantifies the effects of smoking cessation therapies on nicotine craving and self-administration

An exploratory investigation of predictors of outcome in face-to-face and online cognitive-behavioural therapy for bulimia nervosa

September 12, 2022
This study found that improved quality of life, severity of illness symptoms before treatment, and some personality traits were associated with clinical trial outcome in a psychotherapy treatment trial for bulimia nervosa

Baseline anxiety-sensitivity to estradiol fluctuations predicts anxiety symptom response to transdermal estradiol treatment in perimenopausal women – A randomized clinical trial.

September 12, 2022
The menopausal transition is associated with an increased risk of major depression, characterized by anxiety and anhedonia phenotypes. This randomized, double-blind, placebo-controlled trial investigated medically healthy women (46-60 years) in the early or late menopause transition.

Examination of perfectionism and self-concept constructs across stages of eating disorder recovery in men: An exploratory study

September 12, 2022
Higher self-esteem and lower perfectionism were reported by men in recovery from eating disorders, compared to those still ill with symptoms

Metrics to evaluate implementation scientists in the USA: what matters most?

September 12, 2022
This study highlights the importance of examining how implementation scientists are evaluated with regard to tenure and promotion, given the rapid growth of the field and the unique focus of implementation science. Implementation science experts identified a significant mismatch between factors weighted as more important for tenure and promotion (e.g.,...