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Barriers and facilitators to implementing the HEADSS psychosocial screening tool for adolescents living with HIV/AIDS in teen club program in Malawi: health care providers perspectives.

February 9, 2022
Barriers and facilitators to implementing the HEADSS psychosocial screening tool for adolescents living with HIV/AIDS in teen club program in Malawi: health care providers perspectives.

Anticipating mental health needs after chemotherapy in early-stage breast cancer using patient-reported symptom screening

February 9, 2022
Among 149 women with breast cancer, 40% reported at least mild depression and 52% reported at least mild anxiety at the end of chemotherapy. These mental health symptoms at the end of chemotherapy were predictive of future prescriptions for psychiatric medications in the first several years after treatment.

The effects of predator odor (TMT) exposure and mGlu3 NAM pretreatment on behavioral and NMDA receptor adaptations in the brain

February 9, 2022
This work identifies lasting behavioral changes and adaptations in glutamatergic targets in the insular cortex and BNST following a stressor exposure and a role for mGlu3 signaling in some of these changes.

Prior histories of posttraumatic stress disorder and major depression and their onset and course in the three months after a motor vehicle collision in the AURORA study

February 9, 2022
This study examined the degree to which a prior history of depression and PTSD influenced the development of these outcomes in a cohort of individuals (n=1306) presenting to the emergency department after a new index trauma (motor vehicle collision). A prior history of these disorders were dominant risk factors for...

Improving Mental Health Among Transgender Adolescents: Implementing Mindful Self-Compassion for Teens

January 11, 2022
The purpose of this study was to investigate the feasibility, acceptability, and preliminary outcomes of an online self-compassion intervention for transgender adolescents, with the aim of improving mental health. Participants identified as transgender or gender expansive, were between the ages of 13 and 17, and lived in the U.S. or...

Cortisol trajectories measured prospectively across thirty years of female development following exposure to childhood sexual abuse: Moderation by epigenetic age acceleration at midlife

January 7, 2022
Results suggest that childhood sexual abuse is associated with significant HPA axis changes that are associated with accelerated epigenetic aging. Implications for biological embedding models of early life adversity and adult outcomes are discussed.

RTICBM-74 is a brain-penetrant CB1 receptor allosteric modulator that reduces alcohol intake in rats

January 7, 2022
The present works shows that a newly developed negative allosteric modulator of the cannabinoid receptor subtype 1 (CB1) receptor with an excellent pharmacokinetic profile reduces alcohol drinking in rats, suggesting potential therapeutic relevance for the treatment of alcohol use disorder.

Teacher and caregiver perceptions of family engagement in teacher-led task-shifted child mental health care in a low-and-middle-income country.

January 7, 2022
The current study explored teacher and caregiver perceptions of family engagement within a teacher-led, task-shifted mental health intervention in an LMIC. Primary school teachers from five schools in Darjeeling, India delivered evidence-based, indicated mental health care to children with mental health needs throughout the school day. Barriers included logistical challenges...

The Potential Emergence of “Education as Mental Health Therapy” as a Feasible Form of Teacher-Delivered Child Mental Health Care in a Low and Middle Income Country: A Mixed Methods Pragmatic Pilot Study.

January 7, 2022
We assessed task-shifting children’s mental health care to teachers as a potential approach to improving access to child mental health care. Findings support the feasibility of task-shifting children’s mental health care to classroom teachers in resource-limited schools. These findings support the potential emergence of “education as mental health therapy” (Ed-MH)...

Caregiver responsiveness as a mechanism to improve social communication in toddlers: Secondary analysis of a randomized controlled trial

December 3, 2021
This study examined data from a randomized controlled trial to determine whether improvements in child social communication skills were mediated through changes in caregiver responsiveness. Results indicated that as caregiver responsiveness increased over 8 months of intervention, the child’s social communication skills also increased, suggesting that caregiver responsiveness may be...