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Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in post-trauma depression and anxiety following a recent trauma

April 5, 2022
The richness of the AURORA study offered an opportunity to understand why racial/ethnic groups show differences in the prevalence of trauma-related disorders. We observed that Black participants show reduced depression and anxiety symptoms after trauma, despite greater burden of structural inequities, suggestive of psychological resilience to trauma. However, White participants...

Strategies Utilized to Prevent and Control SARS-CoV-2 Transmission in Two Congregate, Psychiatric Healthcare Settings During the Pandemic

March 9, 2022
The COVID-19 pandemic has had a substantial effect on the delivery of psychiatric healthcare. Inpatient psychiatric healthcare facilities have experienced outbreaks of COVID-19, making these areas particularly vulnerable.

Genetic Influences on Longitudinal Trajectories of Cortical Thickness and Surface Area during the First 2 Years of Life

March 9, 2022
Cortical morphology is altered in many psychiatric illness, though little is known about how cortical morphology is develops in early childhood and what factors contribute to it. In this twin study, we found that genetic factors play an important role early childhood development of the cortex.

Scaling Up Patient-Centered Psychological Treatments for Perinatal Depression in the Wake of a Global Pandemic

March 9, 2022
There is a great need to improve access to mental health care for perinatal women. This includes task-sharing among mental health non-specialists, an emphasis on culturally sensitive care, web-based delivery of psychotherapy with some caveats, and a lifespan approach to perinatal mental health. Innovative research efforts are seeking to validate...

Barriers and facilitators to implementing the HEADSS psychosocial screening tool for adolescents living with HIV/AIDS in teen club program in Malawi: health care providers perspectives.

February 9, 2022
Barriers and facilitators to implementing the HEADSS psychosocial screening tool for adolescents living with HIV/AIDS in teen club program in Malawi: health care providers perspectives.

Anticipating mental health needs after chemotherapy in early-stage breast cancer using patient-reported symptom screening

February 9, 2022
Among 149 women with breast cancer, 40% reported at least mild depression and 52% reported at least mild anxiety at the end of chemotherapy. These mental health symptoms at the end of chemotherapy were predictive of future prescriptions for psychiatric medications in the first several years after treatment.

The effects of predator odor (TMT) exposure and mGlu3 NAM pretreatment on behavioral and NMDA receptor adaptations in the brain

February 9, 2022
This work identifies lasting behavioral changes and adaptations in glutamatergic targets in the insular cortex and BNST following a stressor exposure and a role for mGlu3 signaling in some of these changes.

Prior histories of posttraumatic stress disorder and major depression and their onset and course in the three months after a motor vehicle collision in the AURORA study

February 9, 2022
This study examined the degree to which a prior history of depression and PTSD influenced the development of these outcomes in a cohort of individuals (n=1306) presenting to the emergency department after a new index trauma (motor vehicle collision). A prior history of these disorders were dominant risk factors for...

Improving Mental Health Among Transgender Adolescents: Implementing Mindful Self-Compassion for Teens

January 11, 2022
The purpose of this study was to investigate the feasibility, acceptability, and preliminary outcomes of an online self-compassion intervention for transgender adolescents, with the aim of improving mental health. Participants identified as transgender or gender expansive, were between the ages of 13 and 17, and lived in the U.S. or...

Cortisol trajectories measured prospectively across thirty years of female development following exposure to childhood sexual abuse: Moderation by epigenetic age acceleration at midlife

January 7, 2022
Results suggest that childhood sexual abuse is associated with significant HPA axis changes that are associated with accelerated epigenetic aging. Implications for biological embedding models of early life adversity and adult outcomes are discussed.