Category: Research Publications

Brain and behavioral markers at 6 and 12 months of age have shown to be predictive of later autism spectrum disorder (ASD). This work proposes a empirically supported research agenda for the development of a very early intervention for infants at very high likelihood of developing ASD symptoms, that can...

This manuscript reports on an innovative approach to examine brain functional network connectivity using an independent component analysis (ICA)-based approach. We evaluated the approach by studying group differences in the context of a study of resting-state functional magnetic resonance imaging (rsfMRI) data collected from schizophrenia (SZ) individuals and healthy controls...

Adolescence is a period of dynamic neural development, and research has determined that some of the consequences of binge drinking can be long lasting with deficits persisting into adulthood in a variety of cognitive-behavioral tasks. Here we review several of the consequences of adolescent ethanol exposure in light of sex...

Binge alcohol exposure impacts brain function and behavior, and this impact is often more pronounced when it occurs during developmental periods such as adolescence or fetal development. This review focuses on how binge alcohol drinking in people and exposure in animals impairs cognitive flexibility and the brain mechanisms underlying that...

Drs. Asuquo (UNC Gillings School of Public Health), Goodman, Gaynes, and Nakamura propose an adaptation of a collaborative care model for implementation and evaluation of proactive consultation-liaison psychiatry services to improve management of patients with psychiatric conditions who are hospitalized on inpatient medical and surgical services

In this longitudinal study of patients hematologic cancers, Drs. Nakamura, Rosenstein, and colleagues identified that cognitive impairment was common over the 6 months following stem cell transplantation. However, cognition incrementally improved among study participants over time and, of importance, more severe disease and aggressive prior treatment did not impede this...

Self-determination refers to an individual’s capacity and opportunities to act as a causal agent in their own lives to make choices, decisions, and set goals. Both depression and executive function skills were related to self-determination capacity in autistic transition-aged youth, highlighting potential intervention targets to facilitate increased self-determination and potentially...

We validated the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder screen (GAD-7) and Primary Care PTSD screen for DSM-5 (PC-PTSD-5) in a methadone maintenance therapy (MMT) patient population in Hanoi, Vietnam. The prevalence of CMDs in the MMT population was lower than expected. A lower cut-off score may be considered...

We constructed a preliminary model for the natural history of major depression. We determined that the lifetime prevalences are underestimated and the average incidence rates may be underestimated for males. We conclude that recall bias needs to be accounted for in modeling or burden estimates, where the recall bias should...

Increased average daily step count was significantly associated with quality of life in autistic adults with co-occurring intellectual disability.