Category: Research Publications

This paper reported on a new screening tool for children that measures their risk for problematic substance use and other risky behaviors in adolescence. This screening allows children with high risk to receive prevention potentially years before they would otherwise begin problematic behavior.

This study conducted a qualitative analysis of individual interviews and focus groups with caregivers of young people experiencing psychosis to elucidate the challenges associated with navigating the mental healthcare system and providing effective support to their relative. Participants also provided perspectives on desired features and functionality of a digital support...

This scoping review synthesized all interventions that tested either the prevention or improvement of mental health for adolescents living with HIV. It provides valuable insights into improving the mental health of HIV-infected adolescents and can guide further research and practice in this area.

This paper provides the protocol for a pilot trial that will investigate the feasibility, acceptability, fidelity, and preliminary efficacy of a combined youth-friendly suicide prevention and problem-solving intervention in reducing suicidal ideation and behaviors in adolescents living with HIV (ALWH) in Malawi.

This study shows evidence that temporally resolved and functionally contextualized structural basis sets can accurately reflect dynamic functional processes and capture diagnostically relevant structure-functional coupling while detecting nuanced functionally driven structural components that cannot be captured with traditionally computed structural bases. Differential analysis of component stability across repeated scans from...

This study suggest that reduced pyramidal cell excitability is present at baseline in future CHR-Converters, supporting the hypothesis that hypofunction of pyramidal cells is a primary pathology in schizophrenia, rather than a consequence of chronic illness. Positive symptoms among CHR-Converters may reflect compensatory downregulation of inhibition.

This study reveals small but consistent associations between negative symptom dimensions and predominantly prefrontal region cortical thickness, and limbic region volumes. These findings advance our understanding of the network of anatomical regions that may contribute to the severity of negative symptoms in schizophrenia.

Children as young as 5 years old may experience thoughts about suicide, but these behaviors are not well understood. This study involved 98 children 5 to 10 years of age, recruited for potential adversity exposure, and their caregivers, who answered questions about suicidal thoughts and behaviors (STBs) during an in-home...

Black caregivers of children with autism often face a lack of understanding and acceptance within their communities, leading to emotional strain and family tensions around diagnoses and support. This study, based on interviews with 23 caregivers, highlights both the challenges of denial and misinformation as well as the presence of...

In this paper we identified an undescribed channel (GluD1) in the bed nucleus of the stria terminalis (BNST) that leads to cell depolarization and alters the function of excitatory transmission. The BNST is an area of the brain involved in stress and anxiety which suggests that changes in this channel’s...