PRIME: Early Psychosis Research Program
This program was established to better understand the causes, course and treatment of “Clinical High Risk Symptoms”. These symptoms include changes in thinking, mood and perception.
To find out if you might be eligible to participate in one
of our studies, please complete this questionnaire:
People experiencing the following symptoms may be at increased risk for developing an illness like psychosis:
- Confusion about what is real or imaginary.
- Frequent déjà vu.
- Wondering if people can read minds, hear thoughts.
- Mystical/philosophical/religious ideas.
- The familiar feels strange, confusing, threatening, or has special meaning.
- It seems that the mind/eyes/ears are playing tricks or are misperceiving reality (for example mistaking a dog barking for someone calling out a name).
- Changes in perceptual sensitivity–heightened or dulled.
- Unexpected perceptual changes, noises, lights, shadows, geometrical designs, and whispers or hearing one’s name called.
- Increased sensitivity to smells and tastes.
- Notions of being watched, singled out, talked about, or plotted against, even if unsure whether it is true.
- Confused or muddled thinking.
- Using the wrong words, talking about things irrelevant to context of conversations, or going off track.
- Difficulty paying attention or remembering simple things.
- Notions of being especially important, talented, gifted, powerful, or superior to others.
- Decreased interest in spending time or talking with friends or family.
- Less interested in everyday activities or hobbies.
- Prefer to be alone.
Current PRIME Studies
Are Your Thoughts Tangled?
You’re not sure how or why it happened, but you are aware of instances lately when it felt like you had no control over your thoughts. You couldn’t think clearly or concentrate, and you may have even heard or seen things that other people didn’t. While these were unsettling times, you eventually regained control of your thoughts. Still, you may be concerned about whether it will happen again and if it could be a sign of a more serious mental health condition. Because you and others have experienced symptoms like these, local doctors are conducting the 1289-0032 Research Study. In this study, doctors want to evaluate the safety and effectiveness of an investigational drug and compare it to placebo, which looks like the investigational drug but contains no active medication. The investigational drug is not approved to treat any mental health or medical condition. The results of this study will provide more information about the investigational drug and whether it could one day be used to help people who have experienced symptoms similar to yours.
You may be able to participate in this study if you:
• Are 16 to 30 years of age
The study staff will review additional eligibility requirements with you.
All study-related visits, tests, and drugs will be provided at no cost. In
The UNC Department of Psychiatry is conducting a research study to find out more about mental illness. If you have had any of the above symptoms in the past few months, are between 12-30 years old, and have not been diagnosed with psychosis, you may be eligible to participate in a study in the PRIME Research Program.
You may be eligible to receive free study related medical evaluations and monetary compensation. Study participation includes multiple visits lasting 2-8 hours over 2 years. These visits will take place at the University of North Carolina at Chapel Hill.
To see if you may be eligible to participate, please complete the ‘Simple Survey’ at the top right of the page or call (877) PRIME-19 or (877) 774-6319 .
The Project is funded by the National Institute of Mental Health