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Abnormally increased extra-axial cerebrospinal fluid (EA-CSF) volume is present as early as 6 months in infants later diagnosed with autism and is associated with symptom severity at the age of diagnosis, but it is unknown whether early EA-CSF enlargement has long-term impacts on other clinical domains. Executive function (EF) deficits...

This international guideline reviews updated evidence on the safety of low-intensity transcranial electrical stimulation (tES), concluding that it is generally safe and well tolerated across healthy and clinical populations when used within established parameters. It also provides practical recommendations addressing ethical, regulatory, and application standards for research and clinical use.

tECS introduces a new class of brain stimulation: transcranial endogenous current stimulation. Unlike conventional stimulation that applies synthetic rhythms, tECS uses naturalistic, EEG-derived waveforms that mirror the brain’s own dynamics, offering a mechanistic route toward more personalized and biologically informed neuromodulation.

This study examined whether blunted neural reward responsivity uniquely interacted with both individual- and neighborhood-level socioeconomic disadvantage to predict youth depression symptom trajectories. Results showed that youth with blunted reward response at baseline exhibited significant increases in their depression symptoms over an 18-month follow-up if they were also exposed to...

I spent the last 25 years working at the state hospitals in Raleign and Butner.  I am primarily interested in working with patients with schizophrenia spectrum illness.  Throughout my career, I have been involved in teaching and training of residents and medical students and look forward to continuing as I...

Erin is a therapist on the UNC Wake County ACT Team, serving individuals in the community with severe and persistent mental illness. She leads with a person-centered approach, utilizing CBT and DBT to empower individuals to embrace their capabilities and all aspects of themselves to pursue their goals. There is...

Leigh J. Ruth, MD has dedicated her career to the mental health and well-being of children, adolescents, and young adults. With a profound commitment to her patients, Dr. Ruth specializes in treating complex cases involving catatonia, obsessive-compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD), depressive and anxiety disorders, and post-traumatic...

Nicholas Fogleman combines brain imaging research with hands-on clinical care to better understand and support children and teens with ADHD.

This Short Take describes the rationale for, and use of, a decision-making process in community-engaged comparative effectiveness research, co-led by community researchers and academic researchers. The contribution of this methodological guide is to (1) ensure that all partners have a voice in contributing to major study decisions; (2) distribute power...