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Psychiatry Consultation Clinic: A Model that Improves Access to Care and Corresponds to Decreased Anxiety and Depressive Symptoms

December 8, 2025
Description and characterization of an outpatient psychiatry consultation model within a large academic training clinic. The model was associated with observed improvement in depression and anxiety symptoms in those who completed consultation.

Changes in Autism Traits from Early Childhood to Adolescence in the Study to Explore Early Development

December 8, 2025
We investigated predictors of autism traits in the CDC’s Study to Explore Early Development (SEED), one of the largest studies of young autistic children (ages 2–5 years) in the United States. We found that lower levels of cognitive functioning were associated with greater increases in autism traits between early childhood...

Open-label study of the efficacy, safety and tolerability of Brexanolone in the treatment of adult women with postpartum psychosis

December 8, 2025
Postpartum psychosis (PPP) is a rare but severe postpartum psychiatric emergency that occurs during a critical time in mother-infant attachment. This study investigated the efficacy, safety, and tolerability of brexanolone, a neuroactive steroid and synthetic form of allopregnanolone, for adult females with PPP.

Cortical reactive microglia activate astrocytes, increasing neurodegeneration in human alcohol use disorder

December 8, 2025
Microglia are brain cells involved in innate immune responses. This publication finds unique changes in microglia in the post-mortem cerebral cortex of individuals with alcohol use disorder and links them to activation of astrocytes and loss of neurons.

Healthcare Chaplaincy in a Pluralistic Context

December 8, 2025
This special issue for the Journal of Healthcare Chaplaincy examines how chaplaincy is evolving and adapting to provide relevant and critical spiritual care services in a time of increasing religious pluralism. Dr. Nieuwsma oversaw the special issue as the senior associate editor.

Explore brain-inspired machine intelligence for connecting dots on graphs through holographic blueprint of oscillatory synchronization

December 8, 2025
Our work uncovers a unifying synchronization principle behind both brain rhythms and machine intelligence. By modeling neural oscillations and embedding their dynamics into graph neural networks, we develop a new brain-inspired framework (HoloBrain/HoloGraph) that overcomes GNN over-smoothing and enables more powerful reasoning on graphs.

The psychedelic psilocin suppresses activity of central amygdala corticotropin releasing factor receptor 1 neurons and decreases ethanol drinking in female mice

December 8, 2025
This study reveals that psilocin, the active compound in psychedelic mushrooms, reduces alcohol consumption in female mice by suppressing specific stress-related neurons in the brain. These findings offer new insight into the biological mechanisms that may allow psychedelic therapies to effectively treat alcohol use disorder.

Factor Structure of RRBs in Verbal and Non-Verbal Preschoolers With ASD or Related Characteristics

December 8, 2025
Restricted and repetitive behaviors (RRBs) are a core symptom of autism. The current diagnostic system separates RRBs into four domains. These findings suggest that, based on data driven methods, RRBs may be best understood as 3 domains in verbally-able individuals and 2 domains in non-verbal individuals.

Laying the groundwork for a culturally sensitive pediatric primary care eating disorders intervention for the Latino community: insights from focus groups

December 8, 2025
To improve access to care, we are developing and testing First Approach Skills Training- Disordered Eating (FAST-DE), a brief intervention to treat disordered eating in primary care settings. In this study, we conducted focus groups with adolescents and caregivers from the Latino community who had lived experience with disordered eating...

Youth Risk Index: Psychometrics, Predicting Initiation of Early Adolescent Substance Use, and Breadth of Liability Detected

December 8, 2025
This paper reported on a new screening tool for children that measures their risk for problematic substance use and other risky behaviors in adolescence. This screening allows children with high risk to receive prevention potentially years before they would otherwise begin problematic behavior.