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Breaking records at the Walk for Hope 2025!

October 14, 2025
We absolutely knocked it out of the park with fundraising this year for mental illness research through the Walk for Hope!!! With $21,108 raised and 172 participants/donors, we broke our own record by thousands! Thank you so much to all that promoted the event, fundrasied, donated and registered as a...

Dr. Adam Miller speaks with UNC Health about a new study is uncovering ways to assess early suicidal thoughts and behaviors in children as young as 5 –years old.

October 14, 2025
Dr. Adam Miller and his team are now trying to understand how early suicidal thoughts and behaviors emerge in kids. Their findings, published in the Journal of American Academy of Child & Adolescent Psychiatry, show that 34% of children reported passive suicidal ideation (thoughts of dying), and 33% reported active...

Altitudes adaptation and development: Content analysis of experiences and preferences for a digital intervention to support early psychosis caregivers in the United States

October 10, 2025
This study conducted a qualitative analysis of individual interviews and focus groups with caregivers of young people experiencing psychosis to elucidate the challenges associated with navigating the mental healthcare system and providing effective support to their relative. Participants also provided perspectives on desired features and functionality of a digital support...

Evidence-based interventions targeting mental health problems in adolescents living with HIV: a scoping review

October 10, 2025
This scoping review synthesized all interventions that tested either the prevention or improvement of mental health for adolescents living with HIV. It provides valuable insights into improving the mental health of HIV-infected adolescents and can guide further research and practice in this area.

Suicide assessment and feasible evidence-based treatments for adolescents living with HIV in Malawi: Protocol for a pilot randomized controlled trial

October 10, 2025
This paper provides the protocol for a pilot trial that will investigate the feasibility, acceptability, fidelity, and preliminary efficacy of a combined youth-friendly suicide prevention and problem-solving intervention in reducing suicidal ideation and behaviors in adolescents living with HIV (ALWH) in Malawi.

Functionally Adaptive Structural Basis Sets of the Brain: A Dynamic Fusion Approach

October 10, 2025
This study shows evidence that temporally resolved and functionally contextualized structural basis sets can accurately reflect dynamic functional processes and capture diagnostically relevant structure-functional coupling while detecting nuanced functionally driven structural components that cannot be captured with traditionally computed structural bases. Differential analysis of component stability across repeated scans from...

Excitation/inhibition imbalance and conversion to psychosis in the clinical high risk syndrome: Biophysical modeling finds reduced pyramidal cell excitability across EEG paradigms

October 10, 2025
This study suggest that reduced pyramidal cell excitability is present at baseline in future CHR-Converters, supporting the hypothesis that hypofunction of pyramidal cells is a primary pathology in schizophrenia, rather than a consequence of chronic illness. Positive symptoms among CHR-Converters may reflect compensatory downregulation of inhibition.

Neuroanatomical Correlates of Negative Symptoms in Schizophrenia

October 10, 2025
This study reveals small but consistent associations between negative symptom dimensions and predominantly prefrontal region cortical thickness, and limbic region volumes. These findings advance our understanding of the network of anatomical regions that may contribute to the severity of negative symptoms in schizophrenia.

Suicidal Thoughts and Behaviors in Elementary School-Aged Youth: A Pilot Study in 5- to 10-Year-Olds

October 10, 2025
Children as young as 5 years old may experience thoughts about suicide, but these behaviors are not well understood. This study involved 98 children 5 to 10 years of age, recruited for potential adversity exposure, and their caregivers, who answered questions about suicidal thoughts and behaviors (STBs) during an in-home...

Are Antidepressants Safe to Use When You’re Pregnant? Dr. Julia Riddle speaks with Everyday Health

September 30, 2025
About 1 in 5 women experience depression at some point during pregnancy and in the year after giving birth, known as perinatal mood and anxiety disorder (PMAD). Antidepressant use during pregnancy isn’t a question of “safe versus unsafe,” but about balancing the risks of untreated depression with the risks of...