Recent Publications

Feasibility, acceptability, and depression outcomes of a randomized controlled trial of Mindful Self-Compassion for Teens (MSC-T) for adolescents with subsyndromal depression.

Mindful Self-Compassion for Teens, an 8 session program which focuses on cultivating self-compassion as a coping skill for teens, was determined to be feasible, acceptable, and efficacious in preventing the development of clinically significant depression in adolescents with some depressive symptoms.

Facilitated Peer Group Mentoring for Underrepresented Biomedical Researchers: Facilitators’ Experiences and Implications for Dissemination of a Curriculum

Peer group mentoring facilitated by senior faculty represents an effective approach. We explored motivations, benefits, and challenges for facilitators enrolled to deploy an intervention in the context of a randomized controlled trial that tested two peer group mentoring strategies for underrepresented early career researchers.

Early cognitive development and psychopathology in children at familial high risk for schizophrenia

We studied cognitive development and psychopathology in children 4 and 6 years old who where at familial risk for developing schizophrenia and found delayed cognitive development and high rates of symptoms such as anxiety and attention problems, earlier than has previously been described. This indicates that risk for schizophrenia is expressed early in childhood, and … Read more

Research with women sexual assault survivors presenting for emergency care is safe: Results from a multi-site, prospective observational cohort study

A large cohort of 706 women sexual assault survivors presenting to emergency care were recruited nationwide and followed over one year post-assault. Our findings suggested that the vast majority of women rated their research experience as positive (95-97%), denied drawbacks (84-89%), and reported participating was worth it (93-95%), and these positive experiences were stable and … Read more

Analysis of Depression and Anxiety Scores Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Adults With Cystic Fibrosis.

This work examines whether there are changes in the self-report of anxiety and depression symptoms in adults with cystic fibrosis (CF) who started taking elexacaftor/tezacaftor/ivacaftor (E/T/I), a new medication that shows great promise in the treatment of CF. The study found that there were no changes in these symptoms in the overall study population, but … Read more

Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma

Research on resilience after trauma has often focused on individual-level factors (e.g., extensive trauma history) and overlooked influential neighborhood-level factors that may help mitigate the development of posttraumatic stress disorder (PTSD). We applied geospatial analyses to the AURORA Study dataset and evaluated whether greenspace was associated with PTSD trajectories. We found that individuals with greater … Read more

Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps

A deep learning AI model was developed to estimate gestational age (GA) from blind ultrasonography sweeps and incorporated into a low-cost, battery-powered device, aiming to improve pregnancy care in low-resource settings. The study found that novice users, with no prior sonography training, could estimate GA with the AI tool as accurately as credentialed sonographers using … Read more

Schizophrenia genomics: genetic complexity and functional insights

Determining the causes of schizophrenia has been a notoriously intractable problem, resistant to a multitude of investigative approaches over centuries. In recent decades, genomic studies have delivered hundreds of robust findings that implicate nearly 300 common genetic variants (via genome-wide association studies) and more than 20 rare variants (via whole-exome sequencing and copy number variant … Read more

Impact of Cognitive Rehabilitation on Cognitive and Functional Outcomes in Adult Cancer Survivors: A Systematic Review

This is review, led by Dr. Nakamura and in collaboration with an international working group, is the most comprehensive review to date of cognitive rehabilitation interventions to improve cognitive difficulties and daily function in patients with cancer.

From Rhetoric to Action: Justice, Equity, Diversity, and inclusion in Coordinated Specialty Care for Early Psychosis

This Open Forum argues that marginalization and disparities in early psychosis research and clinical care are interrelated, and the authors provide suggestions for paths forward. Commitment to equity and justice demands recentering the perspectives of those most affected by early psychosis services and investing in the integration of historically excluded perspectives across all aspects of … Read more