The UNC Center for Women’s Mood Disorders has a 5-bed inpatient unit for women with moderate to severe postpartum depression (PPD) and perinatal mood disorders. Our unit is the first of its kind in the United States. We are pleased to announce new services! We are now offering evidence-based psychotherapy for the treatment of perinatal mood disorders. Click here for more information.
The UNC Center for Women’s Mood Disorders is directed by Samantha Meltzer-Brody, MD, MPH, the Hayworth Distinguished Professor of Mood Disorders of the UNC Department of Psychiatry and was founded by David Rubinow, MD, Distinguished Professor of Psychiatry. Our faculty are internationally known experts in the evaluation and treatment of women with mood disorders. Reproductive mood disorders include depression and anxiety disorders associated with the reproductive life cycle.
Outpatient Services
The UNC Center for Women’s Mood Disorders offers both clinical and research programs to address the needs of women with reproductive mood disorders.
Clinical Program
Clinical treatment includes assessment, consultation, psychotherapy and medication for women with mood disorders and hormonal disturbance. UNC physicians work with nurses, midwives, counselors and social workers in the community to help create the best plan for managing symptoms. For more information about our specialty clinics and services, visit Patient Care.

Research Program
The research program is expanding to investigate specific areas of women’s reproductive mental health. Clinic patients who are interested can take part in research studies that are designed to investigate the biological basis of women’s reproductive mood disorders and to test new treatments. These studies will focus on a broad spectrum of reproductive psychiatric problems, including menstrually-related mood disorders such as PMS, Premenstrual Dysphoric Disorder (PMDD) and Perimenopausal Depression, as well as pregnancy and postpartum mood disorders. For more information on studies you may qualify for, please visit the Research Studies page.
Inpatient Services
The University of North Carolina at Chapel Hill Perinatal Psychiatry Inpatient Unit has been newly renovated to provide private, state of the art, specialty care for women suffering from severe perinatal psychiatric issues. The unit was newly renovated in June 2011 and is the first of its kind in the United States
Perinatal Psychiatry Inpatient Unit
Our treatment team is comprised of highly trained doctors, nurses, psychologists, midwives, social workers, and other therapists that work together to create individualized treatment plans. We provide comprehensive assessment and treatment, including medication stabilization and a vast range of individual and group therapies as appropriate. Our goal is to provide a supportive environment to assist in the recovery from perinatal psychiatric illness. For more information, please visit the Perinatal Psychiatry Inpatient Unit page.
Reproductive Mood Disorders
- Depression During Pregnancy
- Postpartum Depression (PPD)
- Pregnancy Loss
- Infertility
- Premenstrual Syndrome (PMS)
- Premenstrual Dysphoric Disorder (PMDD)
- Perimenopausal Depression
- Perinatal Psychiatry Inpatient Unit
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