Inside the Lab: News & Events
News
October 18, 2025
We are thrilled to announce that our manuscript titled “Using Precision Medicine Methods to Identify Disease Stages for Chronic Limb-Threatening Ischemia in Participants of the BEST-CLI Trial” has been accepted for publication in the Journal of Vascular Surgery!
This impactful work was led by our talented lab members, Christina Zhou and Molly Hoch, as part of Aim 1 of our R21 grant funded by the NIH. Congratulations to Christina and Molly for this outstanding achievement!
Based on patient- and limb-focused characteristics, we identified three distinct clusters as disease stages. Across the three stages, rates of 2-year mortality were 11.59%, 20.91%, and 24.73% and rates of 2-year amputation-free survival were 83.26%, 70.03%, and 65.82%, respectively, for patients undergoing open bypass. Patients receiving endovascular therapy had 2-year mortality rates of 15.88%, 22.62%, and 20.32% and 2-year amputation-free survival rates of 77.98%, 66.06%, and 67.74%, respectively, for stages 1, 2, and 3. Stage 1 generally included patients who were less likely to have wounds, diabetes, and renal disease. Stage 2 was primarily driven by diabetes and some foot infection. Stage 3 is characterized by high rates of comorbidities, particularly end-stage renal disease and diabetes, as well as higher Wound, Ischemia, and foot Infection grades. Read the full article.
Events
Moussa Shahoud at UNC Research Day.
Moussa Shahoud wins best overall presentation in the epidemiology category.
McGinigle Lab 25/26
The 2nd Annual McGinigle Lab Spring Fling! We have the best team!
Katherine Gray Welch-Mabon presenting at the 20th Annual Academic Surgical Conference
Katharine McGinigle and colleagues at the Vascular Health Innovation Summit in San Francisco.
Katharine McGinigle presenting at the 2023 Diabetic Foot Conference: the annual conference of the American Limb Preservation Society (ALPS).
Katharine McGinigle presenting at The Aortic Session at the Annual Northwestern Vascular Symposium.
Christina Zhou presenting at the Joint Statistical Meeting in Portland, Or.
Podcasts
European Society for Vascular Surgery Podcasts: Translational Spring Meeting Q&A Part 1 with K. McGinigle & J. Raffort-Lareyre
Vaiva Dabravolskaite had a please talking with two extraordinary physicians and scientists: Prof. Katherine McGinigle and Dr. Juliette Raffort-Lareyre. Together we will introduce concepts of machine learning, artificial intelligence and etc and will dive in deeper into different ways it can assist us in predicting risk models for patients with CLTI.
Audible Bleeding Podcast: JVS MTA – Katharine McGinigle – Sex Disparities in Vascular Interventions June 1, 2021
In this “Meet the Author” Episode, Jacob and Matt Chia sit down with Dr. Katharine McGinigle to discuss her article in the June 2021 issue of the JVS titled, “Sex-related disparities in intervention rates and type of intervention in patients with aortic and peripheral arterial diseases in the National Inpatient Sample Database.”
Email Us
katharine_mcginigle@med.unc.edu
Call Us
(919) 966-3392 (Office Phone)
(919) 966-2898 (Fax)
