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Optimizing Antimicrobial Use

Antimicrobial stewardship programs are intended to both slow resistance to antimicrobials and lead to improvements in patient care. Stewardship means acting on the commitment to use antimicrobials only when needed, and when needed, using the right drug, at the right dose, for the right duration. The Carolina Antimicrobial Stewardship Program (CASP) is charged with optimizing the use of antimicrobial agents at the University of North Carolina Hospitals, in partnership with the Outpatient Parenteral Antibiotic Therapy (OPAT) Program once patients transition to outpatient care.


graph show improvement in number and % of abx orders placed in recent months

December 10, 2020

Optimizing Pediatric Perioperative Antibiotics at UNC Children’s

by Bill Wilson, PharmD Last year, a multidisciplinary group (surgery,anesthesiology, perioperative nursing, infectious diseases, and pharmacy) came together to optimize the management and delivery of perioperative antibiotics for pediatric patients. This work group identified gaps in the overall delivery process that they are addressing to bring about positive change for patients. One gap identified early …

image of the front page of the CASP 2020 newsletter The Steward

November 12, 2020

Strategies for optimizing antimicrobials featured in CASP Newsletter

The Carolina Antimicrobial Stewardship Program’s 2020 Newsletter features updates on its efforts, including: Expert advice from CASP’s lead pharmacist Lindsay Daniels in Clinicians’ Corner Pediatric stewardship news from UNC Children’s Hospital’s Zach Willis and Bill Wilson How collaboration with Infection Prevention is expected to help keep C. difficile infection rates low Progress in scaling up …


infographic depicting outcomes from 2-19 to 2020

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UNC Medical Center is a State of North Carolina STAR Partner (read more)