Keywords:
Adult/Peds: Adult, Pediatric* Organism: Bacteria
Keywords: c. diff, c. difficile, fidaxomicin, bezlotoxumab, vancomycin, Clostridioides difficile, CDI, diarrhea, Clostridium difficile
Adult/Peds: Pediatric*
Keywords:
Adult/Peds: Pediatric*
Keywords: This document provides guidance in management, including diagnostic evaluation, antimicrobial therapy, procedural management, and disposition, of children with community-acquired pneumonia (CAP). It is not intended to replace clinician judgment in individual cases; however, it should apply to the vast majority of patients diagnosed with CAP.
Adult/Peds: Pediatric*
Keywords: Hospital-acquired pneumonia (HAP) and Ventilator-associated pneumonia (VAP) are healthcare-acquired conditions with significant risk of morbidity and mortality. Hospitalized patients may have multiple risk factors for pneumonia, such as recumbent position, impaired cough reflex, procedural sedation, immunocompromised status, and/or artificial airways. Prompt recognition of pneumonia in hospitalized patients can prevent serious complications. However, cultures of respiratory secretions are difficult to obtain in patients without an artificial airway or have limited specificity in patients with an endotracheal tube or tracheostomy tube. This guideline document will address the diagnosis and treatment of HAP and VAP in pediatric patients at UNC Children’s. Guidelines for HAP and VAP prevention are maintained separately.
Adult/Peds: Adult, Pediatric* Organism: Bacteria
Keywords: Antimicrobial susceptibility organisms submitted to the University of North Carolina Hospitals Microbiology Laboratory between 1/1/2023 and 12/31/2023. Antibiograms help guide the clinician and pharmacist in selecting the best empiric antimicrobial treatment in the event of pending microbiology culture and susceptibility results.
Adult/Peds: Adult
Keywords: Dosing for Altered Kidney Function Doses should be individualized based on: 1) severity of infection, 2) anticipated drug penetration to site of infection; and 3) size of patient (typical dose for 70 kg patient). All weight-based dosing should be calculated using total body weight (TBW) unless otherwise noted. Calculations for ideal body weight (IBW) and adjusted body weight (adjBW) are included.
Adult/Peds: Adult
Keywords: A blood culture set contains two bottles: one aerobic and one anaerobic. For the recommended two sets of blood cultures for adults, a total of four bottles are needed.
Adult/Peds: Adult Organism: Bacteria
Keywords: community, acquired, CAP
Keywords: Being labeled with a penicillin (PCN) allergy can lead to several negative health outcomes for patients; however, improving documentation of PCN allergies in the electronic medical record can mitigate some of this risk. This guideline provides an overview of the mechanism of penicillin allergy and cross- reactivity between beta-lactams. It also provides guidance for inpatient pharmacists on how to assess, risk-stratify, document the past reaction, and provide recommendations for antibiotic use in the setting of a penicillin allergy.
Adult/Peds: Adult, Pediatric*
Keywords: Restricted anti-infective drugs may be approved by the ID consult services or by the Carolina Antimicrobial Stewardship Program (CASP). Restricted anti-infectives initiated by the ID medicine service (MDK) do not require approval.
Adult/Peds: Adult, Pediatric* Organism: Bacteria
Keywords: CRE, OXA-48, KPC, ceftazidime-avibactam, meropenem-vaborbactam, carbapenem resistant, imipenem-relebactam, cefidericol, B-lactam
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