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Latest News

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    Study points the way to boosting immunotherapy effectiveness against breast cancer and other solid tumors

    Boosting immune system T cells to effectively attack solid tumors, such as breast cancers, can be done by adding a small molecule to a treatment procedure called chimeric antigen receptor-T (CAR-T) cell therapy, according to a study by researchers at the UNC Lineberger Comprehensive Cancer Center. The boost helps recruit more immune cells into battle … Continued

  • Copos and Stanley

    New Faculty Hires

    Calina Copos, PhD Dr. Copos arrived at UNC from the Courant Institute for Mathematical Sciences at New York University. She is a mathematical biologist who uses computational tools to reveal mechanisms in cell biology. She develops mechanical and biochemical theoretical models of single and collective cell migration and self-organization inside cells. These interests are motivated … Continued

  • bioRxiv

    Landscape and Selection of Vaccine Epitopes in SARS-CoV-2

    There is an urgent need for a vaccine with efficacy against SARS-CoV-2. We hypothesize that peptide vaccines containing epitope regions optimized for concurrent B cell, CD4+ T cell, and CD8+ T cell stimulation would drive both humoral and cellular immunity with high specificity, potentially avoiding undesired effects such as antibody-dependent enhancement (ADE)

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Featured Faculty

Adam PalmerAdam Palmer

Dr. Adam Palmer is an Assistant Professor in the Department of Pharmacology and Computational Medicine Program.

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Katherine HoadleyKatherine Hoadley

Dr. Katherine Hoadley is an Assistant Professor in the Department of Genetics and the Lineberger Comprehensive Cancer Center. She was recently published in Cell.

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Leadership

Timothy Elston, PhD
Charles M. Perou, PhD

The School of Medicine has launched a new Computational Medicine Program, aiming to channel UNC’s strength in computational biology, the basic sciences, and clinical research, toward making significant advances in clinical care for patients.

Co-directors of the new program are Timothy Elston, PhD, professor of pharmacology and director of the Curriculum in Bioinformatics and Computational Biology, and Charles M. Perou, PhD, the May Goldman Shaw Distinguished Professor of Molecular Oncology at the UNC Lineberger Comprehensive Cancer Center, and professor of genetics, and of pathology and laboratory medicine.

“The Computational Medicine Program will enable teams of scientists from across the university to come together to address problems related to biomedical research,” Elston said. “Our ultimate goal is to generate models, combining many different types of data, that will enable us to predict outcomes of treatment, and design new ways of thinking about treating disease.”

 

Diversity Statement

The UNC Health Care System and the UNC School of Medicine values all people throughout our organization, regardless of background, lifestyle, and culture. The Computational Medicine Program is committed to workforce diversity and inclusion in a supportive environment.