All cores are observing COVID-19 safety precautions, including physical distancing and use of personal protective equipment. Please contact each core directly for their current status and updates to their operational procedures.
Welcome to UNC Research Core Facilities
UNC Research Core Facilities are shared resources which offer a wide range of services to the research community, including cutting edge technologies, high end instrumentation, technical support, and education. Our facilities are committed to enhancing and expanding the collaborative capabilities of research at UNC-Chapel Hill.
Searchable Core Database
This searchable database lists all the cores in alphabetical order.
You can browse the entire list or use the search function to sort the entire listing either by broad categories, specific keywords, contact name, or equipment.
Core listings by Categories
These pages list our core facilities by general areas of focus: animal models, biochemistry, clinical and translational, genomics, imaging, and research support services. The pages include brief profiles of each core, giving an overview of each to assist the investigator identify the appropriate core to contact for their project. Cores by Categories
Core Facilities on PubMed- A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat February 28, 2021CONCLUSION: This study demonstrates a novel form of cardiomyopathy associated with ALMS1 in the cat. Familial hypertrophic cardiomyopathy is a disease of genetic heterogeneity; many of the known causative genes encoding for sarcomeric proteins. Our findings suggest that variants in genes involved with cardiac development and cell regulation, like the ALMS1 gene, may deserve further […]Kathryn M Meurs
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) February 26, 2021In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy […]Daniel J Klionsky
- CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition February 24, 2021Mucoepidermoid carcinoma (MEC) is a life-threatening salivary gland cancer that is driven primarily by a transcriptional coactivator fusion composed of cyclic AMP-regulated transcriptional coactivator 1 (CRTC1) and mastermind-like 2 (MAML2). The mechanisms by which the chimeric CRTC1/MAML2 (C1/M2) oncoprotein rewires gene expression programs that promote tumorigenesis remain poorly understood. Here, we show that C1/M2 induces […]Adele M Musicant
- Semi-supervised Transfer Learning for Infant Cerebellum Tissue Segmentation February 18, 2021To characterize early cerebellum development, accurate segmentation of the cerebellum into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) tissues is one of the most pivotal steps. However, due to the weak tissue contrast, extremely folded tiny structures, and severe partial volume effect, infant cerebellum tissue segmentation is especially challenging, and the manual […]Yue Sun
- Synergistic learning of lung lobe segmentation and hierarchical multi-instance classification for automated severity assessment of COVID-19 in CT images January 26, 2021Understanding chest CT imaging of the coronavirus disease 2019 (COVID-19) will help detect infections early and assess the disease progression. Especially, automated severity assessment of COVID-19 in CT images plays an essential role in identifying cases that are in great need of intensive clinical care. However, it is often challenging to accurately assess the severity […]Kelei He
- A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat February 28, 2021