News and Updates
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Dr. Michelle Itano’s Neuroscience Microscopy Core featured in CZI blogpost
The past few months have shown how difficult—and how important—it is to be able to understand how a disease really works.
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The Animal Metabolism Phenotyping Core offers technical support and expertise for measuring traits related to metabolism in mouse models of nutrition and disease.
The Animal Metabolism Phenotyping Core offers technical support and expertise for measuring traits related to metabolism in mouse models of nutrition and disease. The core provides access to state-of-the-art methods and equipment to support high quality phenotyping of energy balance in mice.
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UNC CF Tissue Procurement and Cell Culture Core Supports Key SARS-CoV-2 Study
The UNC CF Tissue Procurement and Cell Culture Core, directed by Dr. Scott Randell and managed by Leslie Fulcher contributed to a pivotal study published in Cell by the laboratories of Drs. Richard Boucher and Ralph Baric.
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New Bioinformatics and Analytics Research Collaborative (BARC)
The Bioinformatics and Analytics Research Collaborative (BARC) at the University of North Carolina at Chapel Hill is a multi-disciplinary center that aims to provide bioinformatics expertise and analysis to researchers across the university and beyond for high throughput data.
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Cryo-EM Core Facility Determines High-Resolution Structure of Key DNA-sensing Protein
Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.
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Scientists Show How Brain Flexibility Emerges in Infants
Cognitive flexibility, which refers to the brain’s ability to switch between mental processes in response to external stimuli and different task demands, seems to begin developing during the first two years of life, which is much earlier than previously thought. UNC BRIC researchers led by Weili Lin, PhD, used magnetic resonance imaging techniques to show … Continued
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Quality Management Systems in UNC Core Facilities
The Journal of Biomolecular Techniques has published a paper by Dr. Christopher W. Gregory, Director, Office of Research Technologies (Building a Quality Management System in a Core Facility: A Genomics Core Case Study).
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SOM Biomedical Research Core Voucher Program – FY20 Awarded Projects
120 applications were received in response to the first offering of the SOM Biomedical Research Core Voucher Program. 27 grants were awarded, engaging 19 different cores. FY20 Awarded Projects
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Biomedical Research Core Voucher RFA Program Announcement
The Core Facility Advocacy Committee (CFAC) in the Office of Research Technologies (ORT), UNC School of Medicine (SOM), announces a new program for research projects that directly utilize UNC SOM biomedical research cores. Core vouchers worth up to $10,000 will be awarded to investigators with qualified projects to be used exclusively for core services. Up … Continued
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The Animal Models Core offers CRISPR/Cas9 Genome Editing Services
The Animal Models Core (AMC) offers a full range of CRISPR/Cas9 services for genome editing in mice, rats and cell lines. The core was an early adopter of the CRISPR system in 2013 and have now completed over 150 CRISPR projects. Using the CRISPR System for Genome Editing in Mice and Rats: The CRISPR system … Continued
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Core Facilities Newsletter Summer 2019
Catch up on core facility news and highlights in the newsletter summer 2019 edition
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MSL light sheet microscope enables groundbreaking research
With support from a $200,000 instrumentation grant from the North Carolina Biotechnology Center (NCBC) in 2016, the Microscopy Services Lab (MSL) acquired a light sheet microscope, the only one of this model in the state. “This microscope is unique in its capabilities and it’s transformative in what research it can support,” said Pablo Ariel, Ph.D., … Continued