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Carolina’s Cores of Discovery: New Story from The Well

November 4, 2019

The School of Medicine supports 30 biomedical core facilities that offer researchers a pipeline of services and technologies, and help researchers plan studies, advise on processes, run experiments and analyze biological samples.  Read more about the role of UNC’s shared resources in a new story in “The Well”, the online news source for faculty and … Continued

The Animal Models Core offers CRISPR/Cas9 Genome Editing Services

August 23, 2019

The Animal Models Core (AMC) offers a full range of CRISPR/Cas9 services for genome editing in mice, rats and cell lines. The core was an early adopter of the CRISPR system in 2013 and have now completed over 150 CRISPR projects. Using the CRISPR System for Genome Editing in Mice and Rats: The CRISPR system … Continued

Mouse Behavioral Phenotyping Core

July 29, 2019

The Mouse Behavioral Phenotyping Core, established by the Carolina Institute for Developmental Disabilities, provides testing services, training, and access to an extensive set of automated measurement systems and other resources for behavioral evaluation.  The core can carry out multifaceted testing regimens to characterize mouse models of psychiatric and neurological disorders.  Procedures are available to assess … Continued

MSL light sheet microscope enables groundbreaking research

June 10, 2019

With support from a $200,000 instrumentation grant from the North Carolina Biotechnology Center (NCBC) in 2016, the Microscopy Services Lab (MSL) acquired a light sheet microscope, the only one of  this model in the state.  “This microscope is unique in its capabilities and it’s transformative in what research it can support,” said Pablo Ariel, Ph.D., … Continued

Microscopy Services Laboratory (MSL) Update

May 1, 2019

The Microscopy Services Laboratory’s mission is to help scientists with their research, when it involves light microscopy, electron microscopy and image analysis. We provide training and assistance in all three areas, as well as extensive sample preparation services for transmission and scanning electron microscopy. In consultation with researchers we can advise which instruments will most … Continued

UNC MH Proteomics Center: High-resolution mass analysis of large, intact biomolecules including antibody therapeutics

April 18, 2019

The UNC Proteomics Core receives CFAC funding to acquire a 908 Devices ZipChip Capillary Electrophoresis System. Capillary electrophoresis (CE) is a microfluidic technology that separates a variety of analytes from different matrices based on size and charge. The 908 Devices ZipChip uses a combination of CE and electrospray ionization enabling up-front separation coupled with mass … Continued

Zeng wins Outstanding Individual Performance Award

March 20, 2019

Allergen Biologics created this award due to its first-rate relationship with Xinghua Zeng, the lab manager for the UNC Vector Core, which provides AAV products to researchers around the world. Allergan created a new award category so it could honor UNC School of Medicine’s Xinghua Zeng, MS, the lab manager of the UNC Vector Core. … Continued

RNAi High Throughput Screening Facility

March 20, 2019

RNAi mediated inhibition of gene expression is a powerful method for identifying genes and their cognate phenotype, whose loss of expression alters the cell phenotype. The RNAi High-Throughput Screening (HTS) Facility provides automation and robotics support, guidance in screen assay development, implementation of primary and secondary screens as well as a human genomic siRNA library … Continued