The past few months have shown how difficult—and how important—it is to be able to understand how a disease really works.

The Animal Metabolism Phenotyping Core offers technical support and expertise for measuring traits related to metabolism in mouse models of nutrition and disease. The core provides access to state-of-the-art methods and equipment to support high quality phenotyping of energy balance in mice.

The UNC CF Tissue Procurement and Cell Culture Core, directed by Dr. Scott Randell and managed by Leslie Fulcher contributed to a pivotal study published in Cell by the laboratories of Drs. Richard Boucher and Ralph Baric.

The Bioinformatics and Analytics Research Collaborative (BARC) at the University of North Carolina at Chapel Hill is a multi-disciplinary center that aims to provide bioinformatics expertise and analysis to researchers across the university and beyond for high throughput data.

Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.

Cognitive flexibility, which refers to the brain’s ability to switch between mental processes in response to external stimuli and different task demands, seems to begin developing during the first two years of life, which is much earlier than previously thought. UNC BRIC researchers led by Weili Lin, PhD, used magnetic resonance imaging techniques to show … Read more

The Journal of Biomolecular Techniques has published a paper by Dr. Christopher W. Gregory, Director, Office of Research Technologies (Building a Quality Management System in a Core Facility: A Genomics Core Case Study).