The Animal Metabolism Phenotyping Core offers technical support and expertise for measuring traits related to metabolism in mouse models of nutrition and disease. The core provides access to state-of-the-art methods and equipment to support high quality phenotyping of energy balance in mice.
Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.
Cognitive flexibility, which refers to the brain’s ability to switch between mental processes in response to external stimuli and different task demands, seems to begin developing during the first two years of life, which is much earlier than previously thought. UNC BRIC researchers led by Weili Lin, PhD, used magnetic resonance imaging techniques to show … Continued
120 applications were received in response to the first offering of the SOM Biomedical Research Core Voucher Program. 27 grants were awarded, engaging 19 different cores. FY20 Awarded Projects
The Core Facility Advocacy Committee (CFAC) in the Office of Research Technologies (ORT), UNC School of Medicine (SOM), announces a new program for research projects that directly utilize UNC SOM biomedical research cores. Core vouchers worth up to $10,000 will be awarded to investigators with qualified projects to be used exclusively for core services. Up … Continued
The Animal Models Core (AMC) offers a full range of CRISPR/Cas9 services for genome editing in mice, rats and cell lines. The core was an early adopter of the CRISPR system in 2013 and have now completed over 150 CRISPR projects. Using the CRISPR System for Genome Editing in Mice and Rats: The CRISPR system … Continued