Department of Genetics Publications for May 6-19, 2018

Department of Genetics faculty, postdocs, students and collaborators published nine papers during May 6-19, 2018.

Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes.

Stokowy T, Polushina T, Sønderby IE, Karlsson R, Giddaluru S, Le Hellard S, Bergen SE, Sullivan PF, Andreassen OA, Djurovic S, Hultman CM, Steen VM.

Sci Rep. 2018 May 2;8(1):6915. doi: 10.1038/s41598-018-25280-4.

PMID: 29720671

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus.

Cannon ME, Duan Q, Wu Y, Zeynalzadeh M, Xu Z, Kangas AJ, Soininen P, Ala-Korpela M, Civelek M, Lusis AJ, Kuusisto J, Collins FS, Boehnke M, Tang H, Laakso M, Li Y, Mohlke KL.

G3 (Bethesda). 2017 Sep 7;7(9):3217-3227. doi: 10.1534/g3.117.300088.

PMID: 28754724

Gene Regulation in the 3D Genome.

Li Y, Hu M, Shen Y.

Hum Mol Genet. 2018 May 14. doi: 10.1093/hmg/ddy164. [Epub ahead of print]

PMID: 29767704

A common TCN1 loss-of-function variant is associated with lower vitamin B12 concentration in African Americans.

Hu Y, Raffield LM, Polfus LM, Moscati A, Nadkarni G, Preuss MH, Zhong X, Wei Q, Rich SS, Li Y, Wilson JG, Correa A, Loos RJF, Li B, Auer PL, Reiner AP.

Blood. 2018 May 15. pii: blood-2018-03-841023. doi: 10.1182/blood-2018-03-841023. [Epub ahead of print] No abstract available.

PMID: 29764838

Clinical implications of the non-luminal intrinsic subtypes in hormone receptor-positive breast cancer.

Cejalvo JM, Pascual T, Fernández-Martínez A, Brasó-Maristany F, Gomis RR, Perou CM, Muñoz M, Prat A.

Cancer Treat Rev. 2018 May 7;67:63-70. doi: 10.1016/j.ctrv.2018.04.015. [Epub ahead of print] Review.

PMID: 29763779

Genetic Complexity of Mitral Valve Prolapse Revealed by Clinical and Genetic Evaluation of a Large Family.

Haskell GT, Jensen BC, Skrzynia C, Pulikkotil T, Tilley CR, Lu Y, Marchuk DS, Ann Samsa L, Wilhelmsen KC, Lange E, Patterson C, Evans JP, Berg JS.

J Heart Valve Dis. 2017 Sep;26(5):569-580.

PMID: 29762926

Multicenter Prospective Phase II Trial of Neoadjuvant Dose-Dense Gemcitabine Plus Cisplatin in Patients With Muscle-Invasive Bladder Cancer.

Iyer G, Balar AV, Milowsky MI, Bochner BH, Dalbagni G, Donat SM, Herr HW, Huang WC, Taneja SS, Woods M, Ostrovnaya I, Al-Ahmadie H, Arcila ME, Riches JC, Meier A, Bourque C, Shady M, Won H, Rose TL, Kim WY, Kania BE, Boyd ME, Cipolla CK, Regazzi AM, Delbeau D, McCoy AS, Vargas HA, Berger MF, Solit DB, Rosenberg JE, Bajorin DF.

J Clin Oncol. 2018 May 9:JCO2017750158. doi: 10.1200/JCO.2017.75.0158. [Epub ahead of print]

 PMID: 29742009

Robust Multicategory Support Vector Machines using Difference Convex Algorithm.

Zhang C, Pham M, Fu S, Liu Y.

Math Program. 2018 May;169(1):277-305. Epub 2017 Nov 29.

PMID: 29736090

SETD2 Haploinsufficiency for Microtubule Methylation is an Early Driver of Genomic Instability in Renal Cell Carcinoma.

Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YH, de Cubas AA, Khan A, Davis I, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK.

Cancer Res. 2018 May 3. pii: canres.3460.2017. doi: 10.1158/0008-5472.CAN-17-3460. [Epub ahead of print]

PMID:  29724720