Research Interests
Key words: Rare Disease, Real World Data, Ontologies, Semantics, Precision Medicine
Translational science breaks down traditional silos between scientific disciplines, empowering research innovation and implementation in biomedicine. The Translational and Integrative Sciences Laboratory (TISLab) applies semantic engineering technologies to these varied disciplines to understand the relationship between phenotypes, genetic endowment, and the environment. We aim to accelerate progress and amplify discovery in areas such as rare diseases, long-Covid, Down Syndrome, cancer, and for societal and public health issues such as pandemic response and climate change. TISLab builds global standards to aid communities in advancing their own analytics and is an invested partner in open and team science with diverse contributors.
Mentor Training:
Publications
Melissa Haendel in UNC Genetics News
June 3, 2025
Department of Genetics Publications for April 27th – May 31st, 2025
Department of Genetics faculty, postdocs, students and collaborators published 42 papers during April 27th - May31st 2025.
May 28, 2025
Haendel Lab Publishes New Paper in JMIR Formative Research
Dr. Eric Hurwitz, postdoctoral fellow in the laboratory of Dr. Melissa Haendel (Distinguished Professor, Genetics), is the first author on a new paper titled “Unlocking the potential of wear time of a wearable device to enhance postpartum depression screening and detection: cross-sectional study”, published in the journal JMIR Formative Research.
April 20, 2025
Department of Genetics Publications for March 2nd – 29th, 2025
Department of Genetics faculty, postdocs, students and collaborators published 30 papers during March 2nd - 29th 2025.
March 3, 2025
Department of Genetics Publications for February 2nd – March 1st, 2025
Department of Genetics faculty, postdocs, students and collaborators published 18 papers during February 2nd - March 1st 2025.
November 19, 2024
Haendel Awarded New ARPA-H Subcontract
Dr. Melissa Haendel (Distinguished Professor, Genetics and School of Data Science and Society) has received a new subcontract through University of Alabama at Birmingham (UAB) for an ARPA-H funded grant titled “CHARM: An End-to-End Toolchain for Collecting, Harmonizing, Analyzing, Reasoning about and Manipulating Biomedical Data”.
November 13, 2024
New Contracts, Subcontracts, and Supplements Awarded to Genetics Faculty
New contracts, subcontracts, and supplements awarded to Genetics Faculty Members Dr. Ichiro Misumi, Dr. Marty Ferris, and Dr. Melissa Haendel.
October 28, 2024
Department of Genetics Publications for October 13th – 26th, 2024
Department of Genetics faculty, postdocs, students and collaborators published 13 papers during October 13th - 26th, 2024.
September 14, 2024
Department of Genetics Publications for September 1st-14th, 2024
Department of Genetics faculty, postdocs, students and collaborators published 23 papers during September 1st - 14th, 2024.
September 12, 2024
Dr. Melissa Haendel Receives Leading for IMPACT – Women in Leadership Award
Melissa Haendel, PhD, FACMI (Distinguished Professor, Genetics) was recognized with a 2024 Leading for IMPACT – Women in Leadership Award from FORUM.
August 21, 2024
Dr. Melissa Haendel’s NHGRI RM1 Grant Transferred to UNC Department of Genetics
Melissa Haendel, PhD, FACMI (Distinguished Professor, Genetics) is the contact PI for the recently transferred RM1 grant from NHGRI titled “A phenomics-first resource for interpretation of variants”.