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Associate Professor, Genetics UNC Neuroscience Research Center

Research Interests

Key words: genetics of brain structure and development, neural progenitor cell models, computational biology

Lab Website

We are a lab exploring how variations in the genome change the structure and development of the brain, and in doing so, create risk for neuropsychiatric illness. We study genetic effects on multiple aspects of the human brain, from macroscale phenotypes like gross human brain structure measured with MRI to molecular phenotypes like gene expression and chromatin accessibility measured with genome-sequencing technologies. We also use neural progenitor cells as a modifiable and high fidelity model system to understand how disease-associated variants affect brain development.

Mentor Training:

  • Bias 101
  • Faculty Mentoring Workshop for Biomedical Researchers

Training Program Affiliations:

  • Bioinformatics and Computational Biology
  • Genetics and Molecular Biology
  • Neuroscience

Publications

NCBI Bibliography Link

Lab Members

If you are a grad student interested in a lab rotation, please email me. If you are interested in a postdoc in my lab, please email me with a cover letter and CV containing contact information for at least 3 references.

Jason Stein in UNC Genetics News

Jason Stein