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“Factor VIII inhibitory antibody in a patient with combined factor V/factor VIII deficiency,” a letter to the editor of the journal “Haemophilia” by UNC-Chapel Hill hematologists Tyler Buckner, MD, Brenda Nielsen, MSN, Nigel Key, MD, and Alice Ma, MD, was published online on December 4, 2014.

The letter describes a patient with combined factor V (FV) and FVIII deficiency (F5F8D) who developed severe bleeding complications due to a FVIII inhibitory antibody. To the authors’ knowledge, this is the first time such a complication has been described in F5F8D.

For a complete copy of the letter, see