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By requiring trainees to collaborate with secondary mentors outside of their Field, Department, and/or Institution, the IVB program teaches students to apply molecular, cellular, genetic, and computational approaches to pathological and physiological questions in cell, organ, and whole animal systems; to merge hypothesis- and discovery-based research; to develop high-throughput approaches in cardiovascular models, and to translate their work to clinical settings. Trainees are exposed to the latest concepts in cardiovascular biology by enrolling in advanced paper-based courses specifically designed for UNC’s Graduate Certificate Program In Cardiovascular Science, by attending formal cardiovascular seminars by inside and outside speakers, and by participating in a bi-weekly student-led discussion group. To enhance the skills necessary for effective collaboration and career advancement, Trainees attend program workshops on grant writing, career development, and scientific rigor and responsibility, and they present their data formally at the annual IVB Research Symposium, a trainee-organized event that draws over 120 cardiovascular researchers from the greater Chapel Hill area.