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Clinical Trials

UNC Medical Center is proud to be partnering with Cardiac Dimensions, Inc. to trial the CARILLON Mitral Contour System in patient with functional mitral regurgitation with heart failure symptoms as part of the CARILLON Trial . Our heart team at UNC would be happy to discuss your eligibility to participate. Learn more.

Recent Publications

Sola M, Ramm CJ, Kolarczyk LM, Teeter EG, Yeung M, Caranasos TG, Vavalle JP. Application of a Multidisciplinary Enhanced Recovery After Surgery Pathway to Improve Patient Outcomes After Transcatheter Aortic Valve Implantation. Am J Cardiol. 2016 Aug 1;118(3):418-23.

Arora S, Misenheimer JA, Jones W, Bahekar A, Caughey M, Ramm CJ, Caranasos TG, Yeung M, Vavalle JP. Transcatheter versus surgical aortic valve replacement in intermediate risk patients: a meta-analysis. Cardiovasc Diagn Ther. 2016 Jun;6(3):241-9.

Iyer S, Bauer T, Yeung M, Ramm C, Kiser AC, Caranasos TG, Vavalle JP. A heart team and multi-modality imaging approach to percutaneous closure of a post-myocardial infarction ventricular septal defect. Cardiovasc Diagn Ther. 2016 Apr;6(2):180-4.

Samad Z, Vora AN, Dunning A, Schulte PJ, Shaw LK, Al-Enezi F, Ersboll M, McGarrah RW 3rd, Vavalle JP, Shah SH, Kisslo J, Glower D, Harrison JK, Velazquez EJ. Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunction. Eur Heart J. 2016 Jul 21;37(28):2276-86.

Kiser AC, O’Neill WW, de Marchena E, Stack R, Zarate M, Dager A, Reardon M. Suprasternal direct aortic approach transcatheter aortic valve replacement avoids sternotomy and thoracotomy: first-in-man experience†. Eur J Cardiothorac Surg. 2015 Nov;48(5):778-83

Yadav PK, Halim SA, Vavalle JP. Training in structural heart interventions. J Am Coll Cardiol. 2014 Dec 2;64(21):2296-8.

Recent Presentations

Caranasos TG, Ramm CJ, Daniel K, Hinderliter AL, Vavalle JP. First-in-Man Experience of Using the Aegis Surgical TransitTM System for Suprasternal TAVR Using a Self-Expanding Valve.  Transcatheter Valve Therapies. Chicago Il, 2016.

Howell LA, Sheng, SP, Caughey MC, Yeung M, Sola, M, Vavalle JP. A Global Echocardiography-Based Cardiac Calcification Score Predicts the Presence and Severity of CAD. American College of Cardiology. Chicago Il, 2016.

Jaswaney R, End C, Caughey M, Sudar P, Yeung M, Kaul P, Stouffer GA, Vavalle JP. One-Year Outcomes After Switching From a Bivalirudin-First Strategy to a Heparin-First Strategy For All Percutaneous Coronary Interventions in a Single-Center Cardiac Cathertization Lab. American College of Cardiology, Chicago Il. 2016.

Ramm CJ, Vavalle JP, Nguyen TC, Sampson AJ, Huang P, Foster JA, Thourani VH, Krishnaswamy A, Demyanenko V, Wang TY. Cardiologists Refer Patients with Aortic Stenosis Later and with More Symptoms Than Non-Cardiologists. American College of Cardiology. Chicago, Il.  2016.

Sheng SP, Howell LA, Caughey MC, Yeung M, Vavalle JP. Echocardiography-Based Study of the Effects of Calcification on the Mitral Valve in Patient with Severe Calcific Aortic Stenosis. American College of Cardiology. Chicago, Il, 2016.

Coylewright M, Green P, Dharmarajan K, Vavalle J, Krishnaswamy A, Wang T.  Patients and Their Physicians Do Not Agree on Shared Decision Making in Transcatheter Aortic Valve Replacement.  American College of Cardiology Scientific Sessions. Chicago, Il. 2016.

Vavalle JP, Yeung M, Ramm CJ, Caranasos TG. Successful Percutaneous Closure of a Post-Myocardial Infarction Ventricular Septal Defect Employing a Heart Team and Multi-Modality Imaging Approach.  Miami Valves. October 2015.

Vavalle JP, Caranasos TG, Yeung M, Ramm CJ, Bauer T, Kiser AC. Suprasternal TAVR – First Case in the United States. Transcatheter Valve Therapies. Chicago Il, 2015.