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Virtual Medicine Grand Rounds – Chad Pecot, MD: “Lung Cancer Rewired: Not What You Learned in Med School”
September 30, 2021 @ 12:00 pm - 1:00 pm
I am a tenured Associate Professor and Director of Translational Research at the UNC Lineberger Comprehensive Cancer Center, and I specialize in solid tumor malignancies. As a prior cancer patient, my passion is to uncover important findings in cancer biology and translate these to the clinic as rapidly as possible. Since August 2013 I have been an independent investigator at UNC-Chapel Hill. My research career thus far has quickly led to several high-impact discoveries as a result of innovative ideas and establishment of synergistic collaborative teams. I also have a passion for training the next generation of scientists at the doctorate, post-doctorate, and junior faculty levels. My research is characterized by an integration of therapeutic RNA interference, sophisticated modeling of cancer metastasis and the tumor microenvironment, and leveraging of bioinformatic and systems biology approaches to uncover key nodes in cancer networks. In 2019 I founded EnFuego Therapeutics based on a pipeline of ligand-delivered RNA-based technologies developed in my laboratory, and our long-term goal is to translate these technologies to the clinic. Because metastatic spread accounts for the greatest proportion of cancer-related deaths, most of my current work uses lung and triple-negative breast cancers as disease models with the hopes that our discoveries will also fundamentally impact treatment paradigms in other aggressive malignancies.