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    Research Highlights: Nephrology and Hypertension

    New Research in ANCA Vasculitis This research is a successful collaboration between basic and translational scientists, epidemiologists, geneticists, and nephropathologists. The themes of the projects mirror questions that patients frequently ask: what causes their disease, what will make their disease better or worse, and what will assure that their disease goes into remission and even … Continued

  • Burden and Cost of Diseases in the US

    Research Highlights: Gastroenterology and Hepatology

    The Division of Gastroenterology and Hepatology, and its affiliated Center for Gastrointestinal Biology and Disease, is a national leader in gastrointestinal and liver disease research. In 2018, the Division received more than $23 million in research awards, one of the largest funding bases in UNC’s School of Medicine, including both basic and clinical departments. Remarkably, … Continued

  • community-servings

    Research Highlights: General Medicine and Clinical Epidemiology

    Seth A. Berkowitz investigates ways to address food insecurity in vulnerable patients. Seth A. Berkowitz, MD, MPH, is investigating programs that address food insecurity, for patients with limited or uncertain access to nutritious food because of cost, to consider how they might improve health and healthcare utilization. In one project, Berkowitz is working with Community … Continued

  • Research Highlights: Endocrinology and Metabolism

    Examining the role of dietary fatty acids – Eric Klett, MD Dr. Eric Klett is a physician-scientist whose research interest is in the role of dietary fatty acids, specifically polyunsaturated fatty acids (PUFAs), and their effects on the development of diabetes mellitus. The Klett lab, using pancreatic beta-cell and animal models, examines the role of … Continued

  • Research Highlights: Geriatric Medicine

    Handing Off the Older Patients: Improved Documentation of Geriatrics Assessment in Transitions of Care – Maureen C. Dale, MD Older adults, particularly frail elders, are at an increased risk for poor health outcomes and avoidable re-hospitalization during transitions of care. Nearly one of five older adults are re-hospitalized within 30 days of hospital discharge, and … Continued

  • Research Highlights: Hospital Medicine

    Complex Care Committee Develops Individualized Care Plans – Beth Ann Brubaker, MD   Individualized care plans (ICPs) have been created for patients who are high utilizers of inpatient resources. In some cases this high utilization has been due to fractioned/inefficient medical care and in other cases due to social/addiction issues. Most of these patients have … Continued

  • Research Highlights: Cardiology

    Anil Gehi, MD, Streamlining Triage for AFib Patients to Increase Care Coordination and Prevent Hospitalizations Dr. Anil Gehi’s research focus is on innovative approaches to atrial fibrillation (AFib), from detailed understanding of patient symptomatology, techniques of ablation, processes of care in AFib management, and outcomes research through complex analyses of big data. In 2017, Dr. … Continued

  • Research Highlights: Infectious Diseases

    Mina Hosseinipour Women compromised 59 percent of adults living with HIV in sub-Saharan Africa in 2014 according to the World Health Organization. Creating HIV prevention efforts that target women is critical to stopping new infections. Mina Hosseinipour, MD, MPH, is scientific director of UNC Project-Malawi in Lilongwe, Malawi, and a professor of medicine at UNC. … Continued

  • Research Highlights: Nephrology & Hypertension

    The major areas of research are organized thematically around the following topics; each tab when clicked will reveal more details on each related project. ANCA Vasculitis and Systemic Lupus Erythematosus Glomerular Diseases Diabetic Kidney Disease Epidemiology and Outcomes Research in Kidney Disease Kidney Development and Function Novel Imaging Techniques in Nephrology ANCA Vasculitis and Systemic … Continued

  • Research Highlights: Gastroenterology & Hepatology

    Nicholas Shaheen investigates early detection and treatment of esophageal cancer Nicholas J. Shaheen, MD, MPH, is the Chief of the Division of Gastroenterology and Hepatology. His group is currently involved in more than 50 research studies. Dr. Shaheen’s research focuses on the prevention, detection, and treatment of precancerous and cancerous conditions of the esophagus. He … Continued

  • Research Highlights: General Medicine & Clinical Epidemiology

      Darren DeWalt Investigates Aspirin Dosing for People with Coronary Heart Disease Darren DeWalt, MD, MPH, is the site PI for Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness (ADAPTABLE). In addition to Dr. DeWalt, others in the Department of Medicine that are participating include Joe Rossi in Cardiology and Tim Carey in … Continued

  • Alterations in the composition of gut bacteria can have a significant impact on a person’s health.

    Research Highlights: Rheumatology, Allergy, and Immunology

      Dr. Richard Loeser Conducting First Study To Examine How Diet Alters Gut Bacteria, Potentially Leading to Osteoarthritis The old adage, “you are what you eat,” is proving truer than we ever imagined. New research findings illustrate the negative impact Western diets can have upon the naturally occurring bacteria living in the “gut,” (known as … Continued

  • UNC Diabetes Care members participating in the ADA's Diabetes Dance Dare

    Research Highlights: Endocrinology and Metabolism

      UNC Diabetes Care members participating in the ADA’s Diabetes Dance Dare John Buse leads the diabetes clinical trials operation Dr. Buse was key to high profile work published last year in the New England Journal of Medicine and JAMA that will improve care for diabetics both in achieving glucose control, and limiting cardiovascular disease. … Continued

  • Laura Hanson, MD, MPH

    Research Highlights: Geriatric Medicine

      Laura Hanson, MD, MPH Laura C. Hanson, MD, MPH Dr. Laura Hanson’s primary research interest has been to understand and improve the quality of palliative care for frail elders, with a focus on dementia care and cancer care—work at the intersection of Geriatrics and Palliative Medicine. Finding new ways to deliver high quality care … Continued

  • Ria Dancel, MD, FAAP

    Research Highlights: Hospital Medicine

    Dr. Ria Dancel is dually appointed in the Department of Medicine and the Department of Pediatrics. She is the Director of the Medicine Procedure Service, led by proceduralist attendings working with resident physicians to perform diagnostic and therapeutic bedside procedures. This service was created in 2014 in order to provide efficient and safe procedures and to standardize resident education and…

  • Brian Jensen, MD

    Research Highlights: Cardiology

      Brian Jensen, MD Brian Jensen, MD Dr. Brian Jensen’s clinical and investigative efforts focus on heart failure. The Jensen lab uses animal and cell culture model systems to study the mechanisms of heart injury that lead to the clinical syndrome of heart failure. Dr. Jensen has brought clinical questions from the UNC Heart Failure … Continued

  • David Wohl, MD

    Research Highlights: Infectious Diseases

      David Wohl, MD David Alain Wohl, MD That there are only a handful of Ebola-ologists in the world is something that Dr. Wohl, the Site Leader of the UNC AIDS Clinical Trials Unit at Chapel Hill, realized when the massive Ebola outbreak started to peak in 2014. Ebola raged across West Africa and cases … Continued

  • Satish Gopal, MD, MPH

    Research Highlights: Hematology & Oncology

      Satish Gopal, MD, MPH Satish Gopal, MD, MPH Dr. Gopal went to medical school at Duke University, and trained in medicine-pediatrics at the University of Michigan. He completed medical oncology and infectious diseases fellowships at the University of North Carolina and is board certified in both disciplines. He lived in Tanzania from 2007 until … Continued

  • Jenny Flythe, MD, MPH

    Research Highlights: Nephrology & Hypertension

      Jenny Flythe, MD, MPH Jenny Flythe, MD, MPH Dr. Flythe is a nephrologist and clinical investigator focused on improving clinical outcomes and quality of life for individuals with dialysis-dependent end-stage kidney disease. She joined the UNC School of Medicine faculty in 2014 after completing her nephrology fellowship and public health training at Brigham and … Continued

  • Evan Dellon, MD

    Research Highlights: Gastroenterology & Hepatology

    Evan Dellon, MD Evan Dellon, MD Dr. Evan Dellon’s research focuses on eosinophilic esophagitis (EoE), a chronic allergy/immune-mediated esophageal disease. This condition is characterized by symptoms of esophageal dysfunction and a marked eosinophilic infiltration in the esophageal mucosa, which leads to esophageal strictures and other structural changes. Symptoms of EoE include dysphagia and food impaction … Continued

  • Samuel Cykert, MD

    Research Highlights: General Medicine & Clinical Epidemiology

    Samuel Cykert, MD Samuel Cykert, MD Dr. Cykert’s research career has emphasized access to care, resolution of health disparities in cancer care, and primary care practice improvement including cancer prevention and informatics. He is Clinical Director of the North Carolina Regional Extension Center for Health Information Technology and Director of UNC’s Program on Health and … Continued

  • Jason Mock, MD, PhD

    Research Highlights: Pulmonary & Critical Care Medicine

      Jason Mock, MD, PhD Jason Mock, MD, PhD Dr. Jason Mock is interested in how the lung resolves injury and undergoes repair after damage. In acute or chronic injury the failure to regenerate the lung epithelium plays a role in such processes as pneumonia, pulmonary fibrosis, COPD, aging, and acute respiratory distress syndrome (ARDS). … Continued

  • Richard Loeser, MD, PhD

    Research Highlights: Rheumatology, Allergy, and Immunology

    Richard Loeser, MD, PhD Richard Loeser, MD, PhD Dr. Richard Loeser’s research focuses on understanding basic mechanisms relevant to joint tissue destruction in osteoarthritis. Osteoarthritis (OA) is the primary cause of pain and disability in older adults. A lack of treatments that slow or stop the progression of OA is a major limitation in the … Continued

  • Maya Styner, MD

    Research Highlights: Endocrinology/Metabolism

      Maya Styner, MD Maya Styner, MD Dr. Maya Styner’s lab is interested in how exercise benefits health, specifically bone marrow health. Our bones are not stagnant, rock-like materials – they change throughout life. The marrow within bones contains various kinds of cells, including fat cells. The proportions of these cells can decrease or increase … Continued