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Our clinical trials group hosts a variety of studies focused on HIV and other infectious diseases. We belong to a group of international and local researchers whose combined mission is to find a cure for HIV, reduce the burden of disease due to HIV infection and its complications, and discover new strategies to prevent HIV transmission. We are dedicated to finding new therapies for other infectious diseases such as COVID-19, hepatitis and influenza.

Participation can range from simple, single blood draws to complex, customized treatment therapies – you can decide what is the best fit for you.

Please select the tabs below to learn more about the types of trials we conduct. For information on current studies, please call 919-966-6712.


Acute HIV Infection

These studies are for people who are diagnosed with HIV as soon as two to four weeks after they contract HIV. This is the initial stage of HIV, and it lasts until the body creates antibodies against the virus. These studies are for people who have not started taking medications known as Antiretroviral Therapy (ART) or who have just started on ART. For more information about Acute HIV please click here.

HIV CURE-related Studies

Our group has a number of different studies focused towards bringing us closer to a cure for HIV. While our ultimate goal is to find a way to eradicate HIV, we are not there yet. No one who participates in these studies will be cured but our current studies are exploring different ideas that we hope will put us closer to finding a cure. There are varying levels of participation from a single blood draw to procedures to receiving different medications and personalized therapies. The purpose of these studies is to learn more about how the immune system works, where HIV hides in the body, what medications could flush out HIV from its hiding spots, how we can teach a person’s own immune cells to attack HIV, and vaccines to neutralize HIV replication. Different studies require varying amounts of visits, time commitments, potential risks, and financial compensation. To learn more about HIV CURE research please visit the UNC HIV Cure Center Website here.

HIV Treatment Studies

These particular studies are focused towards individuals who have been diagnosed with HIV. We have a wide variety of studies:

  • HIV treatment studies for people who have been on Antiretroviral medication (ART) for at least one year and have an undetectable viral load
  • HIV treatment studies for those who have difficulty taking Antiretroviral medication (ART) and maintaining viral suppression
  • HIV treatment studies for those who have never taken HIV medication or have stopped for a while

These studies are for people who have been on Antiretroviral medication (ART) for at least one year and have an undetectable viral load.

Some of these studies investigate the effectiveness of new treatment regimens, while others analyze how HIV affects different aspects of a person’s overall health and well-being.

HIV Prevention Studies

These studies are designed to investigate ways of preventing HIV acquisition.

COVID-19 Therapeutics

The University of North Carolina at Chapel Hill is actively working to find safe and effective ways to prevent and treat COVID-19. Without you we will not find a vaccine or cure, thank you for considering taking part in such important work.

We have two different kinds of studies:

Treatment Studies
These are studies that involve taking either a FDA-approved medication for something other than its intended purpose OR an investigational medication to safely and effectively treat a given illness or condition.
These studies typically involve:

  • Taking a medication at different time points
  • Having your blood drawn to monitor safety & your body’s response to the medication
  • Frequent check-ins with a clinician
Observational Studies
These kinds of studies DO NOT involve any sort of intervention (i.e. medication, investigational device, etc.) but rather utilize in-person or remote visits, and sample collection to gather information about a topic of interest.
These studies typically involve:

  • Surveys (either in-person or online)
  • Sample collection (i.e. blood draws, nasal swabs, etc.)