Publications

Selected Publications

2024

McCullough MJ, Bose PG, Mock JR. “Regulatory T Cells: Supporting Lung Homeostasis and Promoting Resolution and Repair after Lung Injury”. International Journal of Biochemistry and Cell Biology. May 2024 PMID: 38518980

McCullough MJ, Tune MK, Cabrera JVC, Torres-Castillo J, He M, Feng Y, Doerschuk CM, Dang H, Beltran AS, Hagan RS, Mock JR. “Characterization of the MT-2 Treg-like cell line in the presence and absence of FOXP3.” Immunol Cell Biol. 2024 March; 102 (3). PMID: 38288547.

2023

Leist SR and Mock JR. “The importance of “negative” results – lipid lessons in coronavirus biology”. Am J Respir Cell Mol Biol. 2023 Dec; 69 (6): 610-611. PMID: 37672661.

Gladstone DE, D’Alessio FR, Howard C, Lye M, Mock JR, Abrams D, Gibbs K, Huang M, Zeng K, Herlihy J, Trevino S, Bassett R, Sadeghi T, Parmar S, Flowers C, Mukherjee S, Thall R, Slutsky AS. “Regulatory T Cell Infusions for Moderate-Severe Acute Respiratory Distress Syndrome due to COVID-19” Blood Advances. March 24, 2023. PMID: 36961352

Mock JR, Tune MK, Bose, PG, McCullough MJ, Doerschuk CM. “Comparison of Different Dosing Methods of Initiating Lung Inflammation and the Sex-Specific Effects on Inflammatory Parameters.” AJP Lung. 2023 Jan 3 PMID: 36594854

2022

Dinnon KH, Leist SR, Okuda K, Dang H, Gully KL, De la Cruz G, Evangelista MD, Takanori A, Gilmore RC, Hawkins PE, Nakano S, West A, Schafer A, Gralinksi LE, Everman JL, Sajuthi SP, Zweigart MR, Dong S, McBride J, Cooley FR, Love MK, Groshong SD, VanSchoiack A, Phelan SJ, Liang Y, Hether T, Leon M, Zumwalt RE, Stroberg E, Barton LM, Duval EJ, Mukhopadhyay S, Borczuk A, Thorne LB, Sakthivel MK, Lee YZ, Hagood J, Mock JR, Seibold MA, O’Neal WK, Montgomery SA, Boucher RC, Baric RS “SARS-CoV-2 Infection Produces Chronic Pulmonary Epithelial and Immune Cell Dysfunction with Fibrosis in Mice” Science Translational Medicine July 7, 2022.  PMID 35857635

2021

Friedman E, Franzone J, Ko ER, Corey K, Mock JR, Alavian N, Schwartz A, Drummond MB, Suber T, Linstrum K, Bain W, Castiblanco SA, Zak M, Zaeh S, Gupta I, Damarla M, Punjabi NM. Rationale and Design of the Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 Patients: the “PRONE” Study. Contemp Clin Trials. 2021 Aug 13; 109:106541. Doi:10.1016/j.cct.2021.106541. PMID: 34400361

Sanders EC, Burkes RM, Mock JR, Brown TT, Wise RA, Hansel NN, Liu MC, Drummond MB. “Bronchoalveolar Lavage and Plasma Cathelicidin Response to 25-Hydroxy Vitamin D Supplementation: A Pilot Study” Chronic Obstr Pulm Dis. May 21, 2021 doi: 10.15326/jcopdf.2021.0220. PMID 34044475

2020

Norton DL, Ceppe A, Tune MK, McCravy M, Devlin T, Drummond MB, Carson SS, Vincent BG, Hagan RS, Dang H, Doerschuk CM, Mock JR. “Bronchoalveolar Tregs are associated with duration of mechanical ventilation in acute respiratory distress syndrome.” J Transl Med 18, 427 (2020). https://doi.org/10.1186/s12967-020-02595-3

Hedrick TL, Murray BP, Hagan RS, Mock JR. “COVID-19: Clean up on IL-6.” Am J Respir Cell Mol Biol. 2020 Oct;63(4):541-543. PMID: 32750259

Mock JR, Dial CF, Tune MK, Gilmore RC, O’Neal WK, Hong D, Doerschuk CM. “The impact of Tregs on the AT2 cell transcriptome during the resolution of acute lung injury and the contributions of IFN-γ.” Am J Respir Cell Mol Biol. 2020 Oct;63(4):464-477. PMID: 32543909

Mock JR, Tune MK, Dial CF, Torres-Castillo J, Hagan RS, Doerschuk CM. “Effects of IFN-γ on immune cell kinetics during the resolution of acute lung injury.” Physiol Rep. 2020 Feb; 8 (3)m e14368. PMID: 32061190

2019

Mock JR, Dial CF, Tune MK, Norton DL, Martin JR, Gomez JC, Hagan RS, Hong D, Doerschuk CM. “Transcriptional Analysis of Foxp3⁺ Regulatory T Cells and Functions of Two Identified Molecules during Resolution of ALI” JCI Insight. 2019 March 21; 4(6). PMID: 30753170

2017

Dial CF, Tune MK, Doerschuk CM, and Mock JR. “Foxp3⁺ Regulatory T Cell Expression of Keratinocyte Growth Factor Enhances Lung Epithelial Proliferation.” 2017 August 1; 57(2) Am. J. Respir. Cell Mol. Biol. PMID: 28296468

2016

Mock JR, Kolb TK, Illei PB, Yang SC, Lederman HM, and Merlo CA. “Bronchus Associated Lymphoid Tissue in Kabuki Syndrome with Associated Hyper-IgM Syndrome/Common Variable Immunodeficiency” Am J Respir Crit Care Med. 2016 Aug 15; 194(4):514-515. PMID: 27275756

Singer BD, Mock JR, D’Alessio FR, Aggarwal NR. Mandke P, Johnston L, Damarla M. “Flow-cytometric method for simultaneous analysis of mouse lung epithelial, endothelial, and hematopoietic lineage cells” Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9) PMID: 26944088

D’Alessio FR, Craig JM, Singer BD, Files DC, Mock JR, Garibaldi BT, Fallica J, Tripathi A, Mandke P, Gans JH, Sidhaye VK, Heller NM, Morris PE, Mitzner W, King LS, Aggarwal NR. “Enhanced Resolution of Experimental ARDS through IL-4 Mediated Lung Macrophage Reprogramming”. Am J Physiol Lung Cell Mol Physiol. 2016 February 19. PMID: 26895644

2015

Limjunyawong N, Mock J, and Mitzner W. “Instillation and Fixation Methods Useful in Mouse Lung Cancer Research” Vis. Exp. 2015 Aug 31 ;( 102), e52964, doi: 10.3791/52964. PMID: 26381993

Singer BD, Mock JR, Garibaldi BT, Aggarwal NR, Sidhaye VK, Florez MA, Chau E, Gibbs KW, Mandke P, Tripathi A, Yegnasubramanian S, King LS, D’Alessio FR. “Regulatory T cell DNA methyltransferase inhibition accelerates resolution of lung inflammation.” Am J Respir Cell Mol Biol. 2015: May; 52(5):641-52 PMID: 25295995

Files DC, Liu C, Pereyra A, Wang Z, Aggarwal NR, D’Alessio FR, Garibaldi BT, Mock JR, Singer BD, Feng X, Lee AL, Philpott S, Lussier S, Purcell L, Chou J, Seeds M, King LS, Morris PE, Delbono O. “Therapeutic Exercise Attenuates Neutrophilic Lung Injury and Skeletal Muscle Wasting.” Sci Transl Med. 2015 Mar 11;7(278):278-32 PMID: 25761888

2014

Mock JR, Garibaldi BT, Aggarwal NR, Jenkins J, Limjunayawong N, Singer BD, Chau E, Rabold R, Files DC, Sidhaye V, Mitzner, W, Wagner EM, King LS, and D’Alessio FR. “Foxp3+ Regulatory T Cells Promote Epithelial Proliferation.” Mucosal Immunol. 2014 Nov;7(6):1440-51 PMID: 24850425