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Marsico Lung Institute/UNC Cystic Fibrosis Center

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MUC5B and DMBT1: An atomic force microscope image of mucus

MUC5B and DMBT1: An Atomic Force Microscope Image of Mucus.

Mucus is a complex biofluid that our cells secrete to create a barrier to protect our bodies from bacteria, viruses, and other pathogens. In the image above, captured by Jerome Carpenter, PhD, the long strands are mucins (in this case most likely MUC5B), which form the structural scaffold of mucus. The long “centipedes” are complexes of a protein called DMBT1, which adheres to several different types of bacteria and viruses. Scale bar = 1 um.


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