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Mathew Sebastian, MD, PhD | Department of Medicine

Mathew Sebastian, MD, PhD

Mathew Sebastian, MD, PhD

About

Mathew is originally from South Carolina and graduated from USC with a degree in biology. After graduation, he went to the NIH as an Intramural Research Fellow in the Laboratory of Immunology in NIAID working with regulatory T cells, a subset of CD4+ T cells that serve to dampen the adaptive immune response. His research at UF has included work with studying the role of Pglyrp3 in regulation of Breast Cancer metastases, the role of copper chaperones in dendritic cells and their role in future immunotherapies, and more recently with a lab focusing on the combination of immune checkpoint blockade and bone marrow derived from hematopoietic stem and progenitor cells in overcoming checkpoint inhibitor resistance in CNS malignancies.

He also has an interest in medical education and published an article summarizing his findings from a study examining how MD-PhD students were currently being trained in clinical research. With his ultimate goal of working as a physician-scientist in the field of Oncology, Mat created a patient-centered research symposium to highlight the importance of basic and translational research as a collaborative effort with the Clinical and Translational Science Institute and invited well known people who had cancer serve as keynote speakers. Mat was recognized for his outstanding dedication to patient care by induction into the Gold Humanism Honor Society.

Mat enjoys running, cooking, and experimenting in the kitchen.

  • Undergraduate

    University of South Carolina Honors College

  • Graduate School

    University of Florida

  • Medical School

    University of Florida