Congratulations to the lab of Jonathan Schisler, MS, PhD, Assistant Professor, Department of Pharmacology, for linking the specific biochemical changes to a protein called CHIP to specific disease characteristics of patients with a wide range of rare disorders.
Dr. Schisler led research showing that limiting the activity of a mutant CHIP protein could decrease symptom severity for people with cerebral ataxia, a debilitating disease of the nervous system. The research is published in the Journal of Biological Chemistry.