Services
Pricing for Media
All prices are per liter of media and subject to change without notice.
Descriptions of Media & Pricing
Media Type |
Description |
Academic Pricing |
Commercial Pricing |
| BEGM Medium | Bronchial epithelial growth medium (BEGM) for expansion of cells on plastic | $325/Liter | $375/Liter |
| ALI Medium | Air/Liquid interface (ALI) medium for differentiation of cells on porous supports | $325/Liter | $375/Liter |
| VALI Medium | Vertex-ALI medium for differentiation of cells on porous supports (contains Ultroser™ G)1 | $500/Liter | $550/Liter |
Pricing for Lung Cells
The MLI Tissue Procurement and Cell Culture Core has experience isolating primary airway epithelial and other cell types from normal, disease control, and CF lungs. Cell pricing is based on one million viable cells, and prices are subject to change without notice.
Cell Descriptions & Pricing
Human Airway Epithelial Cells
Cell Type |
Description |
Academic Pricing |
Commercial Pricing |
| Normal Human Airway Epithelial Cells | Cryopreserved vial of Human Lung Airway Epithelial Cells. No history of prior chronic lung diseases, smoker or non-smoker | $600/Million | $900/Million |
| Diseased Human Airway Epithelial Cells | Cryopreserved vial of Diseased Human Lung Airway Epithelial Cells. History of prior chronic lung disease- (COPD, Asthma) | $600/Million | $900/Million |
| Cystic Fibrosis (CF) Human Airway Epithelial Cells | Cryopreserved vial of Human Airway Epithelial cells. Homozygous severe CFTR mutation- (F508del/F508del) | $800/Million | $2225/Million |
| Cystic Fibrosis (CF) Human Airway Epithelial Cells | Cryopreserved vial of Human Airway Epithelial cells. Heterozygous F508del/second severe CFTR mutation (F508del/Other) | ||
| Cystic Fibrosis (CF) Human Airway Epithelial Cells | Cryopreserved vial of Human Airway Epithelial cells. Non F508del CFTR mutations- (Other CF/Other CF) | ||
| Conditionally Reprogrammed Cells (CRC) – Any CF Mutation | Cryopreserved vial of CRC cells. These cells are isolated and expanded following our standard methods.2 Passage 1 cells are expanded using the CRC methods,3 and passage 2 of converted CRC can be provided. | $960/Million | $2448/Million |
Other Human Lung Cells
Announcement: ****Currently we are not offering human alveolar type II (AT2) epithelial cells or small airway epithelial (SAE) cells. Please check back in the future.****
Cell Type |
Description |
Academic Pricing |
Commercial Pricing |
| Human Lung Microvascular Endothelial Cells | Cryopreserved vial of Human Lung Microvascular Endothelial Cells. Normal or diseased, smoker or non-smoker | $600/Million | $900/Million |
| Human Lung Fibroblast Cells | Cryopreserved vial of Human Lung Fibroblast cells. Normal or diseased, smoker or non-smoker | $600/Million | $900/Million |
| Normal Nasal Epithelial Cells | Cryopreserved vial of Human Normal Nasal Epithelial Cells. Limited supply – please inquire | $600/Million | $1000/Million |
Well-Differentiated Cell Cultures
Prices are based on individual porous membranes and are subject to change without notice.
Cell Type |
Description |
Academic Pricing |
Commercial Pricing |
| Normal HAE Well-Differentiated Cell Cultures | Normal Airway Epithelial cells (passage 2 or 3), cultured in ALI medium on collagen coated porous membrane* (age of maturity~ four weeks) Non-smoker or smoker cells available. | $125/Membrane | $140/12mm Membrane
$280/24mm Membrane |
| Diseased HAE Well-Differentiated Cell Cultures | Diseased Airway Epithelial cells (passage 2 or 3), cultured in ALI medium on collagen coated porous membrane* (age of maturity~ four weeks) COPD or Asthma HAE cells. Check availability. | $125/Membrane | $140/12mm Membrane
$280/24mm Membrane |
*Corning 12 mm Transwell® with 0.4 μm Pore polyester membrane or Millicell Cell culture insert, 12 mm, hydrophilic PTFE, 0.4 μm.
Training
Prices are subject to change without notice.
Product |
Description |
Academic Pricing |
Commercial Pricing |
| MLI Core Training | Daily rate for receiving MLI Tissue Core training on basic Core techniques and protocols | $150/day/person | $250/day/person |
1Neuberger T, Burton B, Clark H, Van Goor F. Use of primary cultures of human bronchial epithelial cells isolated from cystic fibrosis patients for the pre-clinical testing of CFTR modulators. Methods Mol Biol. 2011;741:39-54. doi: 10.1007/978-1-61779-117-8_4. PMID: 21594777. Vertex Pharmaceuticals Incorporated, San Diego, CA 92121, USA.
Ultroser™ G serum substitute can successfully replace FCS (fetal calf serum) in cell culture medium. It is designed for the in vitro culture of anchorage-dependent cells. Please inquire about the availability of this product prior to ordering.
2Fulcher ML, Gabriel S, Burns KA, Yankaskas JR, Randell SH. Well-differentiated human airway epithelial cell cultures. Methods Mol Med. 2005;107:183-206. doi: 10.1385/1-59259-861-7:183. PMID: 15492373.
3Gentzsch M, Boyles SE, Cheluvaraju C, Chaudhry IG, Quinney NL, Cho C, Dang H, Liu X, Schlegel R, Randell SH. Pharmacological Rescue of Conditionally Reprogrammed Cystic Fibrosis Bronchial Epithelial Cells. Am J Respir Cell Mol Biol. 2017 May;56(5):568-574. doi: 10.1165/rcmb.2016-0276MA. PMID: 27983869; PMCID: PMC5449492.
If you do not see a service listed, please contact us for more information.
Prices are subject to change without notice.