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Associate Professor of Orthopaedic Surgery

Orthopaedic Sports Surgery

Medical Degree

Wake Forest University School of Medicine, Winston-Salem, NC


Orthopaedic Surgery, Temple University, Philadelphia, PA; University of North Carolina, Chapel Hill, NC


Orthopaedic Sports Medicine,  University of Connecticut Sports Medicine Program, Farmington, CT

Research Fellowship, Technical University Munich Sports Medicine, Munich

Associate Professor of Orthopaedic Surgery; University of North Carolina, Chapel Hill
Medical Director, UNC Physical Therapy Services
  • Soft tissue trauma of the shoulder and knee
  • Sports medicine
  • ACL repair

UNC Orthopaedics (Carolina Pointe II)
6011 Farrington Road
Suite 201
Chapel Hill, NC 27517

  • Biological scaffolds
  • ACL repair

(see entire list available at PubMed)

Lisee C, Davis-Wilson H, Evans-Pickett A, Horton WZ, Blackburn T, Franz JR, Thoma L, Spang JT, Pietrosimone, Brian. Linking gait biomechanics and daily steps post ACL-reconstruction. Med Sci Sports Exerc. 2022 Jan 21. doi: 10.1249/MSS.0000000000002860. Online ahead of print. PMID: 35072659.

Davis-Wilson HC, Thoma LM, Johnston CD, Young E, Evans-Pickett A, Spang JT, Blackburn JT, Hackney AC, Pietrosimone B. Fewer daily steps are associated with greater Cartilage oligomeric matrix protein response to loading post-ACL reconstruction. J Orthop Res. 2022 Jan 20. doi: 10.1002/jor.25268. Online ahead of print. PMID: 35060165.

Bjornsen E, Schwartz TA, Lisee C, Blackburn T, Lalush D, Nissman D, Spang J, Pietrosimone B. Loading during midstance of gait is associated with magnetic resonance imaging of cartilage composition following anterior cruciate ligament reconstruction. Cartilage. 2022 Jan-Mar;13(1):19476035211072220. doi: 10.1177/19476035211072220. PMID: 35098719.

Howe D, Cone SG, Piedrahita JA, Spang JT, Fisher MB. Age and sex-specific joint biomechanics in response to partial and complete ACL injury in the porcine model. J Athl Train. 2021 Dec 29. doi: 10.4085/1062-6050-565-21. Online ahead of print. PMID: 34964874.

Mars Group. Outcomes of revision anterior cruciate ligament reconstruction in soccer players: a cohort study. Bone Jt Open. 2021 Dec;2(12):1043-1048. doi: 10.1302/2633-1462.212.BJO-2021-0145.R1. PMID: 34905939.

Howe D, Cone SG, Piedrahita JA, Collins B, Fordham LA, Griffith EH, Spang JT, Fisher MB. Sex-specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model. J Orthop Res. 2021 Nov 9. doi: 10.1002/jor.25207. Epub ahead of print. PMID: 34751996.

Cone, SG, Barnes, RH, Howe, D, Fordham, LA, Fisher, MB, Spang, JT. Age- and sex-specific differences in ACL and ACL bundle size during adolescent growth. J Orthop Res. 2021; 1- 8. doi:10.1002/jor.25198

Lisee C, Spang JT, Loeser R, Longobardi L, Lalush D, Nissman D, Schwartz T, Hu D, Pietrosimone B. Tibiofemoral articular cartilage composition differs based on serum biochemical profiles following anterior cruciate ligament reconstruction. Osteoarthritis Cartilage. 2021 Sep 16:S1063-4584(21)00905-5. doi: 10.1016/j.joca.2021.09.005. Epub ahead of print. PMID: 34536530.

Pfeiffer SJ, Spang JT, Nissman D, Lalush D, Wallace K, Harkey MS, Pietrosimone LS, Padua D, Blackburn T, Pietrosimone B. Association of jump-landing biomechanics with tibiofemoral articular cartilage composition 12 months after ACL reconstruction. Orthop J Sports Med. 2021 Jul 21;9(7):23259671211016424. doi: 10.1177/23259671211016424. PMID: 34368382; PMCID: PMC8299897.

MARS Group et al. Spang JT. Association between graft choice and 6-year outcomes of revision anterior cruciate ligament reconstruction in the MARS cohort. Am J Sports Med. 2021 Aug;49(10):2589-2598. doi: 10.1177/03635465211027170. Epub 2021 Jul 14. PMID: 34260326.

Evans-Pickett A, Longobardi L, Spang JT, Creighton RA, Kamath G, Davis-Wilson HC, Loeser R, Blackburn JT, Pietrosimone B. Synovial fluid concentrations of matrix Metalloproteinase-3 and Interluekin-6 following anterior cruciate ligament injury associate with gait biomechanics 6 months following reconstruction. Osteoarthritis Cartilage. 2021 Jul;29(7):1006-1019. doi: 10.1016/j.joca.2021.03.014. Epub 2021 Mar 27. PMID: 33781899.

Nordberg RC, Huebner P, Schuchard KG, Mellor LF, Shirwaiker R A, Loboa EG, & Spang, JT. The evaluation of a multiphasic 3D-bioplotted scaffold seeded with adipose derived stem cells to repair osteochondral defects in a porcine model. Journal of Biomedical Materials Research Part B: Applied Biomaterials. Jun 2021. 109( 12), 2246– 2258.

Wallace KG, Pfeiffer SJ, Pietrosimone LS, Harkey MS, Zong X, Nissman D, Kamath GM, Creighton RA, Spang JT, Blackburn JT, Pietrosimone B. Changes in infrapatellar fat pad volume from 6 to 12 months following anterior cruciate ligament reconstruction and associations with patient-reported knee function. J Athl Train. 2021 Mar 31;56(11):1173–9. doi: 10.4085/1062-6050-0458.20. Epub ahead of print. PMID: 33787883; PMCID: PMC8582630.

Pietrosimone B, Davis-Wilson HC, Seeley MK, Johnston C, Spang JT, Creighton RA, Kamath GM, Blackburn JT. Gait Biomechanics in individuals meeting sufficient quadriceps strength cutoffs following anterior cruciate ligament reconstruction. J Athl Train. 2021 Jan 22. doi: 10.4085/425-20. Epub ahead of print. PMID: 33481020.

Boling MC, Dupell M, Pfeiffer SJ, Wallace K, Lalush D, Spang JT, Nissman D, Pietrosimone B. In vivo compositional changes in the articular cartilage of the patellofemoral joint following anterior cruciate ligament reconstruction. Arthritis Care Res (Hoboken). 2021 Jan 18. doi: 10.1002/acr.24561. Epub ahead of print. PMID: 33460530.

Mahon HS, Spang JT, Kamath GV. Editorial commentary: fluoroscopy is seldom required during knee posterolateral reconstruction. Arthroscopy. 2020 Nov;36(11):2897-2899. doi: 10.1016/j.arthro.2020.09.028. PMID: 33172586.

MARS Group, et al Spang JT. Rate of infection following revision anterior cruciate ligament reconstruction and associated patient- and surgeon-dependent risk factors: Retrospective results from MOON and MARS data collected from 2002 to 2011. J Orthop Res. 2020 Oct 1. doi: 10.1002/jor.24871. Epub 2020 Oct 19. PMID: 33002248; PMCID: PMC7854959.

Pietrosimone B, Luc-Harkey BA, Harkey MS, Davis-Wilson HC, Pfeiffer SJ, Schwartz TA, Nissman D, Padua DA, Blackburn JT, Spang JT. Using TENS to enhance therapeutic exercise in individuals with knee osteoarthritis. Med Sci Sports Exercise. 2020 Oct. [accessed 2020 Sep. 25]; 52(10): 2086-2095. doi:10.1249/MSS.0000000000002353.

MARS Group, et al. Spang JT. Meniscal repair in the setting of revision anterior cruciate ligament reconstruction: results from the MARS cohort. Am J Sports Med. 2020 Aug 21. [accessed 2020 Sep. 25]; doi:10.1177/0363546520948850. Epub 2020 Aug 21. PMID: 32822238.

Blackburn T, Padua DA, Pietrosimone B, Schwartz TA, Spang JT, Goodwin JS, Dewig DR, Johnston CD. Vibration improves gait biomechanics linked to posttraumatic knee osteoarthritis following anterior cruciate ligament injury. J Orthop Res. 2020 Aug 5. [accessed 2020 Sep. 25]; doi:10.1002/jor.24821.

Mellor LF, Nordberg RC, Huebner P, Mohiti-Asli M, Taylor MA, Efird W, Oxford JT, Spang JT, Shirwaiker RA, Loboa EG. Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering applications. J Biomed Mater Res B Appl Biomater. 2020 Jul. [accessed 2020 Sep. 25]; 108(5): 2017-2030. doi:10.1002/jbm.b.34542.

MARS Group et al. Spang JT. Predictors of clinical outcome following revision anterior cruciate ligament reconstruction. J Orthop Res. 2020 Jun; [accessed 2020 Sep. 25]; 38(6): 1191-1203. doi:10.1002/jor.24562.

Davis-Wilson HC, Pfeiffer SJ, Johnston CD, Seeley MK, Harkey MS, Blackburn JT, Fockler RP, Spang JT, Pietrosimone B. Bilateral Gait 6 and 12 Months Post-Anterior Cruciate Ligament Reconstruction Compared with Controls. Med Sci Sports Exercise. 2020 Apr. [accessed 2020 Sep. 25]; 52(4): 785-794. doi:10.1249/MSS.0000000000002208.

Evans-Pickett A., Longobardi L., Spang J.T., Creighton R.A., Kamath G., Davis-Wilson H.C., Loeser R., Blackburn J.T., Pietrosimone B. Synovial Fluid Concentrations of Matrix Metalloproteinase-3 and Interluekin-6 Following Anterior Cruciate Ligament Injury Associate with Gait Biomechanics 6 months Following Reconstruction. Osteoarthritis and Cartilage. March 2020. DOI: 10.1016/j.joca.2021.03.014.

Cone SG, Lambeth EP, Piedrahita JA, Spang JT, Fisher MB. Joint laxity varies in response to partial and complete anterior cruciate ligament injuries throughout skeletal growth. J Biomech. 2020 Mar 5. [accessed 2020 Sep. 25]; doi:10.1016/j.jbiomech.2020.109636.

Huebner P, Warren PB, Chester D, Spang JT, Brown AC, Fisher MB, Shirwaiker RA. Mechanical properties of tissue formed in vivo are affected by 3D-bioplotted scaffold microarchitecture and correlate with ECM collagen fiber alignment. Connect Tissue Res. 2020 Mar. [accessed 2020 Sep. 25]. 61(2): 190-204. doi:10.1080/03008207.2019.1624733.

Blackburn JT, Pietrosimone B, Spang JT, Goodwin JS, Johnston CD. Somatosensory Function Influences Aberrant Gait Biomechanics Following Anterior Cruciate Ligament Reconstruction. Journal of Orthopeadic Research. 2020 Mar; [accessed 2020 Sep. 25]; 38(3): 620-628. doi:10.1002/jor.24495.

North Carolina State Game-Changing Research Incentive Program (GRIP), 2016

GRIP is intended to incentivize and support visionary research ideas that will result in large-scale extramural funding, award-winning research impacts, and first-class interdisciplinary graduate education and training.

Collaborative research group based at North Carolina State and the University of North Carolina.

The O’Donoghue Award, 2014

American Orthopaedics Society for Sports Medicine National Meeting

The best overall paper which deals with clinical based research or human in-vivo research. Awarded to the MARS (Multi-center Anterior Cruciate Ligament Revision Study) research group for the study of revision anterior cruciate ligament surgery.

Frank C. Wilson Faculty Teaching Award, 2011

University of North Carolina Department of Orthopaedics. Awarded by outgoing Chief Residents to the faculty member who has made the greatest contribution to their education at the University of North Carolina.

Albert Trillat Young Investigator Award, 2009

International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine.

This award provides recognition for a young researcher who has done outstanding clinical laboratory research contributing to the understanding, care or prevention of injuries to the knee.

Outstanding Resident Presentation and Paper, 2004

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