UNC Palliative Care investigators are leading research on a variety of topics including:

  • Palliative care for persons with Alzheimer’s disease and related dementias
  • Palliative and supportive care for persons with cystic fibrosis
  • Innovative models for palliative care in cancer
  • Measuring the quality of palliative and hospice care
  • Communication and decision making
  • Supporting parents and young families facing advanced cancer


Recent Research Citations:

Hanson LC, Kistler CE, Lavin K, Gabriel SL, Ernecoff NC, Lin FC, Sachs GA, Mitchell SL. Triggered Palliative Care for Late-stage Dementia: a Pilot Randomized Trial. J Pain Symptom Manage. 2018. [epub ahead of print]

Cohen SM, Volandes AE, Shaffer ML, Hanson LC, Habtemariam D, Mitchell SL. Concordance Between Proxy Level of Care Preference and Advance Directives Among Nursing Home Residents With Advanced Dementia: A Cluster Randomized Clinical Trial. J Pain Symptom Manage. 2018.

Wendlandt B, Ceppe A, Choudhury S, Nelson JE, Cox CE, Hanson LC, Danis M, Tulsky JA, Carson SS. Risk Factors for Post-Traumatic Stress Disorder Symptoms in Surrogate Decision-Makers of Patients with Chronic Critical Illness. Ann Am Thorac Soc. 2018;15(12):1451-1458.

Toles M, Song MK, Lin FC, Hanson LC. Perceptions of Family Decision-makers of Nursing Home Residents With Advanced Dementia Regarding the Quality of Communication Around End-of-Life Care. J Am Med Dir Assoc. 2018;19(10):879-883.

Ernecoff NC, Zimmerman S, Mitchell SL, Song MK, Lin FC, Wessell KL, Hanson LC. Concordance between Goals of Care and Treatment Decisions for Persons with Dementia. J Palliat Med. 2018;21(10):1442-1447.

Dellon EP, Helms SW, Hailey CE, Shay R, Carney SD, Schmidt HJ, Brown DE, Prieur MG. Exploring knowledge and perceptions of palliative care to inform integration of palliative care education into cystic fibrosis care. Pediatric pulmonology. 2018;53(9):1218-1224.

Loizeau AJ, Shaffer ML, Habtemariam DA, Hanson LC, Volandes AE, Mitchell SL. Association of Prognostic Estimates With Burdensome Interventions in Nursing Home Residents With Advanced Dementia. JAMA Intern Med. 2018;178(7):922-929.

Farber JG, Prieur MG, Roach C, Shay R, Walter M, Borowitz D, Dellon EP. Difficult conversations: Discussing prognosis with children with cystic fibrosis. Pediatr Pulmonol. 2018;53(5):592-598.

Li L, Nelson JE, Hanson LC, Cox CE, Carson SS, Chai EJ, Keller KL, Tulsky JA, Danis M. How Surrogate Decision-Makers for Patients With Chronic Critical Illness Perceive and Carry Out Their Role. Crit Care Med. 2018;46(5):699-704.

Ernecoff NC, Wessell KL, Gabriel S, Carey TS, Hanson LC. A Novel Screening Method to Identify Late-Stage Dementia Patients for Palliative Care Research and Practice. J Pain Symptom Manage. 2018;55(4):1152-1158 e1151.

Lamas D, Panariello N, Henrich N, Hammes B, Hanson LC, Meier DE, Guinn N, Corrigan J, Hubber S, Luetke-Stahlman H, Block S. Advance Care Planning Documentation in Electronic Health Records: Current Challenges and Recommendations for Change. J Palliat Med. 2018;21(4):522-528.

Chisholm L, Zimmerman S, Rosemond C, McConnell E, Weiner BJ, Lin FC, Hanson LC. Nursing home staff perspectives on adoption of an innovation in goals of care communication. Geriatr Nurs. 2018;39(2):157-161.

Austin CA, Choudhury S, Lincoln T, Chang LH, Cox CE, Weaver MA, Hanson LC, Nelson JE, Carson SS. Rapid Response Events in Hospitalized Patients: Patient Symptoms and Clinician Communication. J Pain Symptom Manage. 2018;55(3):946-952.

Dolin R, Silberman P, Kirk DA, Stearns SC, Hanson LC, Taylor DH Jr, Holmes GM. Do Live Discharge Rates Increase as Hospices Approach Their Medicare Aggregate Payment Caps? J Pain Symptom Manage. 2018;55(3):775-784.

DiMartino LD, Birken SA, Hanson LC, Trogdon JG, Clary AS, Weinberger M, Reeder-Hayes K, Weiner BJ. The influence of formal and informal policies and practices on health care innovation implementation: A mixed-methods analysis. Health Care Manage Rev. 2018.

Bloomberg BA, Mulligan RC, Staub SJ, Hanson LC, Drickamer MA, Dale MC. Handing Off the Older Patient: Improved Documentation of Geriatric Assessment in Transitions of Care. J Am Geriatr Soc. 2018;66(2):401-406.

Freeman AT, Wood WA, Fox A, Hanson LC. Access to Palliative Care Consultation and Advance Care Planning for Adults with High-Risk Leukemia. J Palliat Med. 2018;21(2):225-228.

Sudore RL, Heyland DK, Lum HD, Rietjens JA, Korfage IJ, Ritchie CS, Hanson LC, Meier DE, Pantilat SZ, Lorenz K, Howard M. Outcomes That Define Successful Advance Care Planning: A Delphi Panel Consensus. J Pain Symptom Manage. 2018;55(2):245-255 e248.

Zheng NT, Li Q, Hanson LC, Wessell KL, Chong N, Sherif N, Broyles IH, Frank J, Kirk MA, Schwartz CR, Levitt AF. Nationwide Quality of Hospice Care: Findings From the Centers for Medicare & Medicaid Services Hospice Quality Reporting Program. J Pain Symptom Manage. 2018;55(2):427-432 e421.

Ernecoff NC, Stearns SC. Costs at the End of Life: Perspectives for North Carolina. N C Med J. 2018;79(1):43-45.

DiMartino LD, Weiner BJ, Hanson LC, Weinberger M, Birken SA, Reeder-Hayes K, Trogdon JG. Inpatient Palliative Care Consultation and 30-Day Readmissions in Oncology. J Palliat Med. 2018;21(1):62-68.

Hailey CE, Yopp JM, Deal AM, Mayer DK, Hanson LC, Grunfeld G, Rosenstein DL, Park EM. Communication with children about a parent’s advanced cancer and measures of parental anxiety and depression: a cross-sectional mixed-methods study. Support Care Cancer. 2018;26(1):287-295.

Hanson LC, Collichio F, Bernard SA, Wood WA, Milowsky M, Burgess E, Creedle CJ, Cheek S, Chang L, Chera B, Fox A. Integrating Palliative and Oncology Care for Patients with Advanced Cancer: A Quality Improvement Intervention. J Palliat Med. 2017;20(12):1366-1371.

DiMartino LD, Weiner BJ, Hanson LC, Weinberger M, Birken SA, Reeder-Hayes K, Trogdon JG. The impact of two triggered palliative care consultation approaches on consult implementation in oncology. Healthc (Amst). 2017.

Dellon EP, Goggin J, Chen E, Sabadosa K, Hempstead SE, Faro A, Homa K. Defining palliative care in cystic fibrosis: A Delphi study. J Cyst Fibros. 2017.

Nelson JE, Hanson LC, Keller KL, Carson SS, Cox CE, Tulsky JA, White DB, Chai EJ, Weiss SP, Danis M. The Voice of Surrogate Decision-Makers. Family Responses to Prognostic Information in Chronic Critical Illness. Am J Respir Crit Care Med. 2017;196(7):864-872.

Check DK, Park EM, Reeder‐Hayes KE, Mayer DK, Deal AM, Yopp JM, Rosenstein DL, Hanson LC. Concerns underlying treatment preferences of advanced cancer patients with children. Psychooncology. 2017;26(10):1491-1497.

Toles M, Colon-Emeric C, Naylor MD, Asafu-Adjei J, Hanson LC. Connect-Home: Transitional Care of Skilled Nursing Facility Patients and their Caregivers. J Am Geriatr Soc. 2017;65(10):2322-2328.

Chen E, Homa K, Goggin J, Sabadosa KA, Hempstead S, Marshall BC, Faro A, Dellon EP. End-of-life practice patterns at U.S. adult cystic fibrosis care centers: A national retrospective chart review. J Cyst Fibros. 2017.

Mitchell SL, Palmer JA, Volandes AE, Hanson LC, Habtemariam D, Shaffer ML. Level of Care Preferences Among Nursing Home Residents With Advanced Dementia. J Pain Symptom Manage. 2017;54(3):340-345.

Bennett AV, Lee S, Drier S, Wessell KL, Hanson LC. A Library of Instruments Endorsed by Published Systematic Reviews for Assessing Patients and Their Care Developed by the Palliative Care Research Cooperative. J Palliat Med. 2017;20(9):910-911.

Dellon EP, Goldfarb SP, Hayes D, Sawicki GS, Wolfe J, Boyer D. Pediatric lung transplantation and end of life care in cystic fibrosis: Barriers and successful strategies. Pediatric Pulmonology. 2017;52(S48).

Song PH, Beyhaghi H, Sommer J, Bennett AV. Symptom burden and life challenges reported by adult chordoma patients and their caregivers. Qual Life Res. 2017;26(8):2237-2244.

Lavin K, Davydow DS, Downey L, Engelberg RA, Dunlap B, Sibley J, Lober WB, Okimoto K, Khandelwal N, Loggers ET, Teno JM. Effect of Psychiatric Illness on Acute Care Utilization at End of Life From Serious Medical Illness. J Pain Symptom Manage. 2017;54(2):176-185 e171.

Hanson LC, Zimmerman S, Song MK, Lin FC, Rosemond C, Carey TS, Mitchell SL. Effect of the Goals of Care Intervention for Advanced Dementia: A Randomized Clinical Trial. JAMA Intern Med. 2017;177(1):24-31.

Miller SC, Lima JC, Intrator O, Martin E, Bull J, Hanson LC. Specialty Palliative Care Consultations for Nursing Home Residents With Dementia. J Pain Symptom Manage. 2017;54(1):9-16 e15.

Dolin R, Holmes GM, Stearns SC, Kirk DA, Hanson LC, Taylor DH Jr, Silberman P. A Positive Association Between Hospice Profit Margin And The Rate At Which Patients Are Discharged Before Death. Health Aff (Millwood). 2017;36(7):1291-1298.

Dolin R, Hanson LC, Rosenblum SF, Stearns SC, Holmes GM, Silberman P. Factors Driving Live Discharge From Hospice: Provider Perspectives. J Pain Symptom Manage. 2017;53(6):1050-1056.

Sudore RL, Lum HD, You JJ, Hanson LC, Meier DE, Pantilat SZ, Matlock DD, Rietjens JA, Korfage IJ, Ritchie CS, Kutner JS. Defining Advance Care Planning for Adults: A Consensus Definition From a Multidisciplinary Delphi Panel. J Pain Symptom Manage. 2017;53(5):821-832 e821.

Rosemond C, Hanson LC, Zimmerman S. Goals of Care or Goals of Trust? How Family Members Perceive Goals for Dying Nursing Home Residents. J Palliat Med. 2017;20(4):360-365.

Park EM, Check DK, Song MK, Reeder-Hayes KE, Hanson LC, Yopp JM, Rosenstein DL, Mayer DK. Parenting while living with advanced cancer: A qualitative study. Palliat Med. 2017;31(3):231-238.

Platts-Mills TF, Richmond NL, LeFebvre EM, Mangipudi SA, Hollowell AG, Travers D, Biese K, Hanson LC, Volandes AE. Availability of Advance Care Planning Documentation for Older Emergency Department Patients: A Cross-Sectional Study. J Palliat Med. 2017;20(1):74-78.

Ernecoff NC, Cox CE. Spirituality, Palliative Care, and the Intensive Care Unit. A New Approach. Am J Respir Crit Care Med. 2017;195(2):150-152.

Winzelberg GS, Hanson LC. Intensive Care Unit Bed Availability and Use of Mechanical Ventilation in Nursing Home Residents With Advanced Dementia: When We Build It, Why Do They Come? JAMA Intern Med. 2016;176(12):1816-1817.

Park EM, Deal AM, Yopp JM, Edwards TP, Wilson DJ, Hanson LC, Rosenstein DL. End-of-life experiences of mothers with advanced cancer: perspectives of widowed fathers. BMJ Support Palliat Care. 2016;6(4):437-444.

Miller SC, Dahal R, Lima JC, Intrator O, Martin E, Bull J, Hanson LC. Palliative Care Consultations in Nursing Homes and End-of-Life Hospitalizations. J Pain Symptom Manage. 2016;52(6):878-883.

Hanson LC, Song MK, Zimmerman S, Gilliam R, Rosemond C, Chisholm L, Lin FC. Fidelity to a behavioral intervention to improve goals of care decisions for nursing home residents with advanced dementia. Clin Trials. 2016;13(6):599-604.

Miller SC, Lima JC, Intrator O, Martin E, Bull J, Hanson LC. Palliative Care Consultations in Nursing Homes and Reductions in Acute Care Use and Potentially Burdensome End-of-Life Transitions. J Am Geriatr Soc. 2016;64(11):2280-2287.

Mayer DK, Deal AM, Crane JM, Chen RC, Asher GN, Hanson LC, Wheeler SB, Gerstel A, Green M, Birken S, Rosenstein DL. Using Survivorship Care Plans to Enhance Communication and Cancer Care Coordination: Results of a Pilot Study. Oncol Nurs Forum. 2016;43(5):636-645.

Toles M, Colon-Emeric C, Asafu-Adjei J, Moreton E, Hanson LC. Transitional care of older adults in skilled nursing facilities: A systematic review. Geriatr Nurs. 2016;37(4):296-301.

Park EM, Deal AM, Check DK, Hanson LC, Reeder-Hayes KE, Mayer DK, Yopp JM, Song MK, Muriel AC, Rosenstein DL. Parenting concerns, quality of life, and psychological distress in patients with advanced cancer. Psychooncology. 2016;25(8):942-948.

Carson SS, Cox CE, Wallenstein S, Hanson LC, Danis M, Tulsky JA, Chai E, Nelson JE. Effect of Palliative Care-Led Meetings for Families of Patients With Chronic Critical Illness: A Randomized Clinical Trial. JAMA. 2016;316(1):51-62.

Song MK, Ward SE, Hanson LC, Metzger M, Kim S. Determining Consistency of Surrogate Decisions and End-of-Life Care Received with Patient Goals-of-Care Preferences. J Palliat Med. 2016;19(6):610-616.

Metzger M, Song MK, Ward S, Chang PP, Hanson LC, Lin FC. A randomized controlled pilot trial to improve advance care planning for LVAD patients and their surrogates. Heart Lung. 2016;45(3):186-192.

Jiron M, Pate V, Hanson LC, Lund JL, Jonsson Funk M, Sturmer T. Trends in Prevalence and Determinants of Potentially Inappropriate Prescribing in the United States: 2007 to 2012. J Am Geriatr Soc. 2016;64(4):788-797.

Hanson LC. A Diamond in the Rough. J Palliat Med. 2016;19(4):346-347.

Kamal AH, Bull J, Ritchie CS, Kutner JS, Hanson LC, Friedman F, Taylor DH Jr, AAHPM Research Committee Writing Group. Adherence to Measuring What Matters Measures Using Point-of-Care Data Collection Across Diverse Clinical Settings. J Pain Symptom Manage. 2016;51(3):497-503.

Song MK, Ward SE, Lin FC, Hamilton JB, Hanson LC, Hladik GA, Fine JP. Racial Differences in Outcomes of an Advance Care Planning Intervention for Dialysis Patients and Their Surrogates. J Palliat Med. 2016;19(2):134-142.

Basch E, Deal AM, Kris MG, Scher HI, Hudis CA, Sabbatini P, Rogak L, Bennett AV, Dueck AC, Atkinson TM, Chou JF. Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial. J Clin Oncol. 2016;34(6):557-565.

Mariano C, Hanson LC, Deal AM, Yang H, Bensen J, Hendrix L, Muss HB. Healthcare satisfaction in older and younger patients with cancer. J Geriatr Oncol. 2016;7(1):32-38.

Dellon EP, Chen E, Goggin J, Homa K, Marshall BC, Sabadosa KA, Cohen RI. Advance care planning in cystic fibrosis: Current practices, challenges, and opportunities. J Cyst Fibros. 2016;15(1):96-101.

Song MK, Ward SE, Fine JP, Hanson LC, Lin FC, Hladik GA, Hamilton JB, Bridgman JC. Advance care planning and end-of-life decision making in dialysis: a randomized controlled trial targeting patients and their surrogates. Am J Kidney Dis. 2015;66(5):813-822.

Gurschick L, Mayer DK, Hanson LC. Palliative Sedation: An Analysis of International Guidelines and Position Statements. Am J Hosp Palliat Care. 2015;32(6):660-671.

Mayer DK, Green M, Check DK, Gerstel A, Chen RC, Asher G, Wheeler SB, Hanson LC, Rosenstein DL. Is there a role for survivorship care plans in advanced cancer? Support Care Cancer. 2015;23(8):2225-2230.

Austin CA, Mohottige D, Sudore RL, Smith AK, Hanson LC. Tools to Promote Shared Decision Making in Serious Illness: A Systematic Review. JAMA Intern Med. 2015;175(7):1213-1221.

Kutner JS, Blatchford PJ, Taylor DH Jr, Ritchie CS, Bull JH, Fairclough DL, Hanson LC, LeBlanc TW, Samsa GP, Wolf S, Aziz NM, Currow DC, Ferrell B, Wagner-Johnston N, Zafar SY, Cleary JF, Dev S, Goode PS, Kamal AH, Kassner C, Kvale EA, McCallum JG, Ogunseitan AB, Pantilat SZ, Potenoy RK, Prince-Paul M, Sloan JA, Swetz KM, Von Gunten CF, Abernethy AP. Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: a randomized clinical trial. JAMA Intern Med. 2015;175(5):691-700.

Zimmerman S, Cohen L, van der Steen JT, Reed D, van Soest-Poortvliet MC, Hanson LC, Sloane PD. Measuring end-of-life care and outcomes in residential care/assisted living and nursing homes. J Pain Symptom Manage. 2015;49(4):666-679.

Wood WA, Deal AM, Bennett AV, Mitchell SA, Abernethy AP, Basch E, Bailey C, Reeve BB. Comparison of seven-day and repeated 24-hour recall of symptoms in the first 100 days after hematopoietic cell transplantation. J Pain Symptom Manage. 2015;49(3):513-520.

Kistler CE, Hess TM, Howard K, Pignone MP, Crutchfield TM, Hawley ST, Brenner AT, Ward KT, Lewis CL. Older adults’ preferences for colorectal cancer-screening test attributes and test choice. Patient Prefer Adherence. 2015;9:1005-1016.

Kamal AH, Hanson LC, Casarett DJ, Dy SM, Pantilat SZ, Lupu D, Abernethy AP. The quality imperative for palliative care. J Pain Symptom Manage. 2015;49(2):243-253.

Faurot KR, Jonsson Funk M, Pate V, Brookhart MA, Patrick A, Hanson LC, Castillo WC, Sturmer T. Using claims data to predict dependency in activities of daily living as a proxy for frailty. Pharmacoepidemiol Drug Saf. 2015;24(1):59-66.

Cagle JG, Zimmerman S, Cohen LW, Porter LS, Hanson LC, Reed D. EMPOWER: an intervention to address barriers to pain management in hospice. J Pain Symptom Manage. 2015;49(1):1-12.

Jackson LC, Hanson LC, Hayes M, Green M, Peacock S, Corbie-Smith G. They lift my spirit up: stakeholders’ perspectives on support teams for African Americans facing serious illness. Health Educ Behav. 2014;41(6):599-604.

Hanson LC, Bull J, Wessell K, Massie L, Bennett RE, Kutner JS, Aziz NM, Abernethy A. Strategies to support recruitment of patients with life-limiting illness for research: the Palliative Care Research Cooperative Group. J Pain Symptom Manage. 2014;48(6):1021-1030.

Park EM, Raddin RS, Nelson KM, Hamer RM, Mayer DK, Bernard SA, Rosenstein DL. Conducting an antidepressant clinical trial in oncology: challenges and strategies to address them. Gen Hosp Psychiatry. 2014;36(5):474-476.

Green MA, Lucas J, Hanson LC, Armstrong T, Hayes M, Peacock S, Elliot-Bynum S, Goldmon M, Corbie-Smith G. Carrying the burden: perspectives of African American pastors on peer support for people with cancer. J Relig Health. 2014;53(5):1382-1397.

Song MK, Hanson LC, Gilet CA, Jo M, Reed TJ, Hladik GA. Management of ethical issues related to care of seriously ill dialysis patients in free-standing facilities. J Pain Symptom Manage. 2014;48(3):343-352.

Hanson LC. Where will palliative care go next? J Palliat Med. 2014;17(9):980-981.

Schenck AP, Rokoske FS, Durham D, Cagle JG, Hanson LC. Quality measures for hospice and palliative care: piloting the PEACE measures. J Palliat Med. 2014;17(7):769-775.

Hanson LC, Green MA, Hayes M, Diehl SJ, Warnock S, Corbie-Smith G, Lin FC, Earp JA. Circles of Care: Implementation and Evaluation of Support Teams for African Americans With Cancer. Health Educ Behav. 2014;41(3):291-298.

Rietjens JAC, Voorhees JR, van der Heide A, Drickamer MA. Approaches to suffering at the end of life: the use of sedation in the USA and Netherlands. J Med Ethics. 2014;40(4):235-240.

Einterz SF, Gilliam R, Lin FC, McBride JM, Hanson LC. Development and testing of a decision aid on goals of care for advanced dementia. J Am Med Dir Assoc. 2014;15(4):251-255.

Raddin RS, Park EM, Hamer RM, Nelson KM, Mayer DK, Rosenstein DL, Bernard SA. A pilot study to evaluate symptom-oriented selection of antidepressants in patients with cancer. J Palliat Med. 2014;17(2):167-175.

Ersek M, Sefcik JS, Lin FC, Lee TJ, Gilliam R, Hanson LC. Provider staffing effect on a decision aid intervention. Clin Nurs Res. 2014;23(1):36-53.

Park EM, Raddin RS, Nelson K, Hamer RM, Mayer DK, Bernard SA, Rosenstein DL. Integrating Psychiatry into Palliative Medicine: Lessons Learned from Our Antidepressant Trial. Journal of Palliative Medicine. 2013;16(11):1326-1326.

Fischberg D, Bull J, Casarett D, Hanson LC, Klein SM, Rotella J, Smith T, Storey CP Jr, Teno JM, Widera E, HPM Choosing Wisely Task Force. Five Things Physicians and Patients Should Question in Hospice and Palliative Medicine. J Pain Symptom Manag. 2013;45(3):595-605.

Beyea A, Fischer J, Schenck A, Hanson LC. Integrating palliative care information and hospice referral in medicaid primary care. J Palliat Med. 2013;16(4):376-382.