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FDA Grants Breakthrough Device Designation for Non-Invasive Brain Stimulation Device to Treat Major Depressive Disorder

March 11, 2025

White matter microstructure in school-age children with down syndrome

March 7, 2025
This was the first study to examine white matter microstructure in school-aged children with Down Syndrome. A spatially specific pattern of results indicated a dissociation between intra- and inter-hemispheric pathways, which could inform more targeted interventions and clinical trials in Down Syndrome.

O-GalNAc glycans are enriched in neuronal tracts and regulate nodes of Ranvier

March 7, 2025
This research describes how a unique class of sugar molecules in the brain is enriched a specialized structures called nodes of Ranvier. This work provides new insight to a group of genes that are involved with genetic disorders of the brain, including schizophrenia.

Building a two-state learning healthcare system for persons with first episode psychosis

March 7, 2025
This paper describes the learning health system model used to create Connection Learning Healthcare System (CLHS): a network of academic institutions, state behavioral health systems, and early psychosis specialty care programs in Pennsylvania and Maryland. It reviews lessons learned and areas of ongoing attention.

The effects of estradiol on subcortical brain volumes in perimenopausal-onset depression​​​​​​

March 7, 2025
Estrogen treatment during menopause increased right hippocampal volumes in women without depression. In women with depression, decreases in right hippocampal volumes predicted decreases in mood symptoms following estrogen treatment.

Neuronal oscillations and functional connectivity of paced nostril breathing: A high-density EEG study

March 7, 2025
We investigated how different breathing techniques impact electrical activity in the brain.

Penaskovic Selected as Interim Chair Department of Psychiatry

March 6, 2025
Kenan Penaskovic, MD, has been selected to serve as interim chair of the Department of Psychiatry. He will assume the role on March 24 from Samantha Meltzer-Brody, MD, MPH, who was announced earlier this year as the new executive dean for the School of Medicine. Dr. Penaskovic currently serves as...

One of the largest psychotherapy trials in the world has implications for transforming mental health care during pregnancy and after birth

March 3, 2025
Toronto, ON (March 3, 2025) – Approximately one in five pregnant and postpartum individuals experience depression and anxiety, yet less than 10 per cent receive proper treatment. To address this problem, a team of interdisciplinary researchers from Canada and the United States investigated if talk therapy can be effectively delivered by...

Welcome, Dr. Alison Roland to the Bowles Center for Alcohol Studies!

February 14, 2025

Welcome, Dr. Jennifer Gates!

February 11, 2025