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Drs. Charguia & Pflum speak with UNC Health Talk about Teen Mental Health and Social Media

July 18, 2024

UNC REACH clinic featured as Dr. Michael Baca-Atlas speaks with WRAL

July 16, 2024

The final unit of our new Youth Behavioral Hospital is open!

July 12, 2024
3 YBH is a 14-bed inpatient unit that evaluates, treats, and monitors young adults (18-21) who need acute psychiatric stabilization.

Probing the neurocardiac circuit in trauma and posttraumatic stress

July 11, 2024
This study probed the neurocardiac circuit by examining associations among its core regions in the brain (e.g., hypothalamus) and the periphery (heart rate [HR], high frequency heart rate variability [HF-HRV], and blood pressure [BP]). Participants were 315 trauma-exposed adults enrolled from emergency departments as part of the prospective AURORA study....

Polygenic risk, childhood abuse and gene x environment interactions with depression development from middle to late adulthood: A U.S. national life-course study.

July 11, 2024
Utilizing national longitudinal data, this study examined how polygenic depression risk and childhood abuse interactively influence the life-course development of depressive conditions from middle to late adulthood. The results revealed that Increasing polygenic depression scores were associated with elevated CES-D levels and potential risks of clinical depression. Non-maltreated females generally...

A novel method for quantifying affective sensitivity to endogenous ovarian hormones

July 11, 2024
Increased sensitivity to ovarian hormone changes is implicated in the etiology of reproductive mood disorders across the female lifespan, including menstrually-related mood disorders, perinatal mood disorders, and perimenopausal depression. We developed a novel method to accurately quantify sensitivity to endogenous hormone fluctuations that may facilitate the prediction and prevention of...

Cross-Frequency Coupling as a Biomarker for Early Stroke Recovery

July 11, 2024
This work highlights the utility of prefrontomotor cross-frequency coupling as a potential motor status and recovery biomarker in stroke. The frequency- and region-specific neurocircuitry featured in this work may also facilitate novel treatment strategies in stroke.

The effects of psychotherapy for anhedonia on subcortical brain volumes measured with ultra-high field MRI

July 11, 2024
This exploratory analysis examined the effects of psychotherapy on subcortical brain volumes. Psychotherapy for anhedonia was not accompanied by changes in subcortical brain volumes. However, there was a modest relation between pre-treatment anhedonia and change in caudate nucleus volumes during treatment.

Ferret as a model system for studying the anatomy and function of the prefrontal cortex: A systematic review

July 11, 2024
Here, we provide a summary of all published research pertaining to the frontal and/or prefrontal cortex of the ferret across research scales. By doing so, we hope to improve clarity in the interpretation of both previous and future publications on the comparative study of frontal cortex.

Christian Hendershot, PhD Clinical Trial on Semaglutide Shows Promise for Treatment of Alcohol Use Disorder, Warrants Further Trials

June 27, 2024