Author Archives: samweiss

This review emphasizes the significant therapeutic potential of neuroactive steroids in modulating TLR signaling pathways, particularly in addressing inflammatory processes associated with neuropsychiatric disorders. It advances our understanding of the complex interplay between neuroactive steroids and immune responses, paving the way for personalized treatment strategies tailored to individual needs and...

This study explored how PTSD symptoms impact future substance use, including tobacco, alcohol, and cannabis, utilizing causal forests to identify what factors are most important in stratifying this relationship. Findings revealed a significant association between PTSD symptoms and heightened tobacco and alcohol use, and that variables for lifetime cigarette use,...

The ALICBCT tool offers an open-source, fully automated method for accurately placing landmarks in cone-beam CT scans, leveraging a novel AI approach for landmark detection with high precision and swift processing times, validated for clinical and research use.

This study developed and tested a novel, interpretable AI-based classifier for assessing the severity of alveolar bone defects in CLP patients using 3D surface models and 2D CNNs, achieving high accuracy and providing visual explanations for its decisions.

This study presents a unique method for analyzing 3D shapes through 2D CNNs with custom pooling, aimed at identifying high-risk ASD subjects by analyzing brain measurements mapped onto a sphere, featuring a novel icosahedron convolution operator and generating explainability maps that corroborate and potentially expand on existing ASD research.

Mullin et al., report that behavioral differences in motor, cognitive, and language developmental trajectories from 6 to 24 months of age in children with autism compared to children with fragile X syndrome. This study highlights an earlier onset of global cognitive delays in fragile X and, conversely, a protracted period...

This editorial overviews the 2023 Intellectual and Developmental Disabilities Research Centers (IDDRCs) Special Issue in the Journal of Neurodevelopmental Disorders. The series focuses on the complex genetics of neurodevelopmental and neuropsychiatric conditions.