Baseline anxiety-sensitivity to estradiol fluctuations predicts anxiety symptom response to transdermal estradiol treatment in perimenopausal women – A randomized clinical trial.
September 12, 2022
The menopausal transition is associated with an increased risk of major depression, characterized by anxiety and anhedonia phenotypes. This randomized, double-blind, placebo-controlled trial investigated medically healthy women (46-60 years) in the early or late menopause transition.