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We propose that the best chance to discover biomarkers and treatment targets for psychiatric illness is to investigate the relationship between a specific symptom, the correlated mental activity, and the correlated neural activity signature.

Goal directed behavior and reward evaluation were found to be linked with distinct neural oscillations. Furthermore, mood symptoms of depression appear to be related to reward-evaluation and motivation symptoms appear to be related to goal-directed behavior.

Response to paper suggesting the precise mechanism for depressive symptom reduction in closed-loop deep brain stimulation could be illuminated by a dynamical systems approach.

A pilot trials investigating the effect of tACS in treating auditory hallucinations in people with schizophrenia.

This is one of the first studies to examine the use of a medication to minimize cognitive changes that may occur during chemotherapy for breast cancer.

Participants (n=2,021) used wrist wearables for 8 weeks after experiencing a traumatic event. Based on accelerometry data, reduced 24-hour activity variance identified individuals with greater pain severity. Changes in several rest-activity measures were associated with changes in pain, sleep, and anxiety over time. Simple thresholds for these biomarkers identified individuals...

In a review of clinical trials done since 2010, we found that in-person treatment for depression is no different from virtual treatment in terms of symptom remission. Virtual treatments included both telehealth with a mental health provider and fully automated internet-based treatments.