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The Role of Intraoperative Radiation in Early-stage Breast Cancer

December 13, 2021
Lead Author: David Ollila, MD | Journal: Clinical Breast Cancer Intraoperative radiation therapy (IORT) is a specialized form of accelerated partial breast irradiation in which a single dose of radiation is delivered to the tumor bed at the time of breast conserving surgery.

Perceived Versus Objective Change in Walking Ability in Peripheral Artery Disease: Results from 3 Randomized Clinical Trials of Exercise Therapy

December 13, 2021
Author: Melina R. Kibbe, MD | Journal of American Heart Association Background In people with lower-extremity peripheral artery disease, the effects of exercise on patient-reported outcomes remain unclear.

Randomized Phase II Study of PET Response-Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial

December 13, 2021
Author: Michael O. Meyers | Journal of Clinical Oncology To evaluate the use of early assessment of chemotherapy responsiveness by positron emission tomography (PET) imaging to tailor therapy in patients with esophageal and esophagogastric junction adenocarcinoma.

Use and disparities in parathyroidectomy for symptomatic primary hyperparathyroidism in the Medicare population

December 13, 2021
Resident Author: Josh Herb, MD | Faculty Author: Lawrence Kim, MD | Journal: Surgery Few studies assess use of parathyroidectomy among older adults with symptomatic primary hyperparathyroidism. Our objective was to determine national usage and disparities in parathyroidectomy for symptomatic primary hyperparathyroidism among insured older adults.

Male sex, ostomy, infection, and intravenous fluids are associated with increased risk of postoperative ileus in elective colorectal surgery

December 13, 2021
Surgery Author: Muneera R. Kapadia, MD | Surgery Journal Postoperative ileus is a common and costly complication after elective colorectal surgery. Effects of intravenous fluid administration remain controversial, and the effect of ostomy construction has not been fully evaluated. Various restrictive intravenous fluid protocols may adversely affect renal function. We...

Socioeconomic factors in timing of esophagectomy and association with outcomes

December 13, 2021
Residency Author: Kevin A. Chen, MD | Faculty Author: Michael O Meyers | Journal of Surgical Oncology Disparities in esophageal cancer are well-established. The standard treatment for locally advanced esophageal cancer is chemoradiation followed by surgery. We sought to evaluate the association between socioeconomic factors, time to surgery, and patient...

Pulmonary complications observed in patients with infective endocarditis with and without injection drug use: An analysis of the National Inpatient Sample

December 13, 2021
Authors: Gita N. Mody, MD, John S. Ikonomidis, MD, Jason M. Long | Journal: PLoS One The impact of cardiovascular and neurologic complications on infective endocarditis (IE) are well studied, yet the prevalence and significance of pulmonary complications in IE is not defined. To better characterize the multifaceted nature of...

Pathology and Molecular Characteristics of Pancreatic Cancer

December 13, 2021
Residency Author: Joseph F Kearney, MD | Faculty Author: Jen Jen Yeh, MD | Journal: Surgical Oncology Clinics of North America Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. However, it should be kept in mind that there are other pancreatic cancers that are classified by...