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TARC Research Seminar: Dr. Brian Diekman; “DNA Damage and Cellular Senescence in Osteoarthritis Pathophysiology.”

December 16, 2022 @ 12:00 pm - 1:00 pm

DNA damage and cellular senescence in osteoarthritis pathophysiology.

Brief Description: Aging is the largest risk factor for osteoarthritis, but the mechanisms responsible for this relationship are unclear. Damaged cells can convert to a phenotypic state known as cellular senescence, and senescent cells are associated with compromised tissue function. This talk will focus on our efforts to understand the accumulation of DNA damage in chondrocytes during aging, and to assess whether the activation of more efficient DNA damage repair has promise as a strategy to limit cellular senescence and osteoarthritis.

Dr. Brian Diekman
Assistant Professor of Biomedical Engineering
UNC-CH & NC State Joint Department of BME

Attend Live in TARC Dickson Conference Room, or via Zoom:

Meeting ID: 978 4115 8212
Passcode: 922015
One tap mobile:
+13017158592,,97841158212#,,,,*922015# US (Washington DC)
+13052241968,,97841158212#,,,,*922015# US




December 16, 2022
12:00 pm - 1:00 pm
Event Category: