Key Collaborators
We collaborate with many leading scientists at UNC and other institutions. These collaborations enhance the research and training environment in our lab. We are particularly grateful to the following friends and colleagues for their important contributions to our projects:
Satoshi Tateishi PhD (Kumamoto University, Japan)
Lab web site: http://www.imeg.kumamoto-u.ac.jp/en/bunya_top/department_of_cell_maintenance/staff/
Dr. Tateishi discovered RAD18, the proximal E3 ubiquitin ligase that activates TLS. Satoshi is a long-standing collaborator and we have co-authored many articles with him.
Hisao Masai PhD (Tokyo Metropolitan Institute of Medical Sciences, Japan)
Lab web site: http://www.cbms.k.u-tokyo.ac.jp/english/lab/rinsho.html#masai
Dr. Masai is a leader in the DNA replication field and has made particular contributions to our understanding of the essential protein kinase CDC7. We worked with Hisao and his lab to define new ways in which TLS is coordinated with S-phase and checkpoint signaling via CDC7 (Day et al., J Cell Biology 2010).
Ken Pearce PhD (UNC)
Lab web site: http://cicbdd.web.unc.edu/directory/kenneth-pearce/
Dr. Pearce has extensive experience in protein chemistry and drug discovery. We are collaborating with Ken and his team to elucidate the protein-protein interaction mechanisms that regulate TLS (e.g. Gao et al., Nature Communications 2016).
Dale Ramsden PhD (UNC)
lab web site: http://ramsdenlab.web.unc.edu/
Dr. Ramsden is a leading DNA repair researcher who has a particular interest in DNA double-strand break repair. We worked with Dale’s lab to elucidate genetic interactions between RAD18 and other DNA repair factors (Yang et al., J Cell Biology 2017)
Ben Major PhD (UNC)
lab web site: http://cancer.unc.edu/majorlab/people.php
Dr. Major studies cell signaling in cancer using diverse approaches including proteomics, systems biology and molecular biology. We collaborated with Ben’s lab to identify a novel mechanism of TLS pathway activation in cancer cells (Gao et al., Nature Communications 2016)
Di Wu (UNC)
Lab web site: http://bcb.unc.edu/faculty-member/di-wu/
Dr. Wu is a computational biologist with whom we are collaborating to define mutagenic consequences of TLS.
Scott Williams PhD (UNC)
Lab web site: https://www.scottwilliamslab.com/
Dr. Williams is a developmental biologist with particular expertise in skin. We are working with Scott to study how TLS impacts carcinogenesis.