The gene, Arl13b, is necessary for the proper construction of the cerebral cortex. The finding offers new insights on normal brain development and illuminates some of the factors behind Joubert’s syndrome, a rare neurological disorder.
The Angelman Syndrome Foundation (ASF) has awarded $1.25 million to six research grants focused on finding treatments and defining the optimal window for treatment for individuals with Angelman syndrome
Spencer Smith, PhD, assistant professor of cell biology and physiology, and the UNC Neuroscience Center, will use the additional funding to pursue experiments to shed light on the role of dendrites in neuron function and computation.
This discovery has implications for how people perceive hot and cold temperatures and for why people with certain forms of chronic pain experience heightened responses to cold temperatures.
The findings could lead to new mental health therapies for disorders such as addiction, anxiety, and depression.
Professor Edvard Moser and Professor May-Britt Moser are director and co-director, respectively, of the Kavli Institute for Systems Neuroscience and they jointly lead the Centre for the Biology of Memory at the Norwegian University of Science and Technology (NTNU) in Trondheim, Norway.
Study suggests L-DOPA therapy for Angelman syndrome may have both benefits and unanticipated effects
New research from UNC provides a neurological justification for this therapeutic approach, but researchers caution there could be unanticipated effects.
Anton lab publishes in Development Cell on how interneurons navigate during the development of the cerebral cortex
UNC researchers track a gene’s crucial role in orchestrating the placement of neurons in the developing brain. Their findings help unravel some of the mysteries of Joubert syndrome and other neurological disorders.
"In a life ended too early, she made key scientific gains"
250 neuroscientists gathered for the 13th Annual UNC Neuroscience Symposium held October 25, 2012
A new activity-dependent role for the protein heavily implicated in autism, Neuroligin-1, identified
Larysa Pevny, PhD, Associate Professor of Genetics, member of the UNC Neuroscience Center, and Director of the UNC Center for Stem Cell Biology and Regenerative Medicine, passed away on Sept. 30, 2012. She was a pioneer in the fields of neuroscience and stem cell biology and is remembered as a brilliant, generous and supportive colleague.
MEK Is a Key Regulator of Gliogenesis in the Developing Brain
13th Annual UNC Neuroscience Symposium Speakers
Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance
6/7/12: Philpot lab publishes in Neuron about an Underlying Cause for Seizures in Angelman syndrome patients
New research by scientists at the University of North Carolina School of Medicine may have pinpointed an underlying cause of the seizures that affect 90 percent of people with Angelman syndrome (AS), a neurodevelopmental disorder.
The Perl prize carries a $10,000 award and is given to recognize a seminal achievement in neuroscience. Past recipients have included four subsequent winners of the Nobel Prize for Physiology and Medicine.
UNC researchers will attempt to understand the cognitive disabilities in patients with RAS/MARK syndromes.
March 2012 - Assistant professor Spencer Smith receives a Career Development Award from the Human Frontier Science Program, an international organization funded by the governments of the G7 nations.
3/22/12: Stuber Lab publishes paper in Neuron - Study shines light on brain mechanism that controls reward enjoyment
In the March 22nd issue of Neuron, a research article fro the Stuber lab shows that activation of VTA GABA neurons can disrupt reward-related behavior by their direct regulation of neighboring dopamine neurons.