Program Alumni

 

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Graduates of the Molecular and Cellular Pathology Program
Class composite images of our alumni can be viewed here

 

2013

Patricia Casbas Hernandez, Ph.D.
Dissertation title: In vitro Coculture Models to Study Heterotypic Interactions in Breast Cancer Microenvironments
Advisor: Melissa Troester

 

Michael Durando, Ph.D.
Dissertation title: Novel DNA Damage Tolerance Mechanisms Mediated by Translesion Synthesis
Advisor: Cyrus Vaziri

 

Meghan Free, Ph.D.
Dissertation title: Role of Circulating T Cells in Autoimmune Kidney Disease: Implications for ANCA Disease and Minimal Change Disease
Advisor: Ronald J. Falk

 

2012

Jessica C. Cardenas, Ph.D.
Dissertation title: The Role of p16INK4a Expression in the Age-related Risk of Venous Thromboembolism
Advisor: Frank C. Church

 

David A. Detwiler, Ph.D.
Dissertation title: Isolation and Characterization of Primary Canine Satellite Cells in the GRMD Model
Advisor: Joe Kornegay

 

Aleeza J. Roth, Ph.D.
Dissertation title: Characterization of Antigenic Determinants and Their Correlation with Disease Activity in ANCA Glomerulonephritis
Advisor: Ronald J. Falk

2011

 

Rachel Beaulieu Goldsmith, Ph.D.
Dissertation title: Detection and Mechanistic Comparison of Two Anti-Trypanosomal Diamidines in a Rat Renal Model
Advisor: Richard T. Tidwell

Lance A. Johnson, Ph.D.
Dissertation title: Apolipoprotein E in Diabetic Dyslipidemia and Atherosclerosis
Advisor: Nobuyo N. Maeda


Kellie Rae Machlus, Ph.D.
Dissertation title: Pathophysiology of Plasma Hypercoagulability in Thrombosis
Advisor: Alisa S. Wolberg


Troy A. McEachron, Ph.D.

Dissertation title: Regulation of Urokinase Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Murine Breast Cancer Cells
Advisor: Frank C. Church


Jessica E. Rodriguez, Ph.D.
Dissertation title: Muscle Ring Finger-1 (MuRF1) Inhibits PPARα Activity to Modulate Cardiac Metabolism
Advisor: Monte S. Willis


Lisa L. Samuelson, M.S.
Thesis title: Sca-1 Positive Pancreatic Progenitor Cells: A Replacement for Transplanted Islets
Advisor: David A. Gerber


Rupninder Sandhu, Ph.D.
Dissertation title: Hypermethylator Phenotype in Human Breast Cancer: Therapeutic Target and Mechanism of DNMT3b Dysregulation
Advisor: William B. Coleman

2010


Jason Thomas Doherty, Ph.D.
Dissertation title: Focal Adhesion Kinase and ARHGAP26 in Cardiac and Skeletal Muscle Development
Advisor: Joan M. Taylor

Mark W. Gramling, Ph.D.
Dissertation title: Serine Proteases and Serine Protease Inhibitors in Breast Cancer Cell Pathophysiology
Advisor: Frank C. Church

Mehmet Karaca, Ph.D.
Dissertation title: Androgen Receptor Activation by Ack1
Advisor: Young E. Whang

Matthew Douglas Medlin, Ph.D.
Dissertation Title: Sphingosine-1-Phosphate and the RGS RhoGEFs Regulate Vascular Smooth Muscle Phenotype
Advisor: Christopher P. Mack

Elizabeth Parker Merricks, Ph.D.
Dissertation title: Cardiovascular Disease, Endothelial Cell Gene Expression, and Renal Dysfunction in Insulin Resistant, Hyperlipidemic Swine
Advisor: Timothy C. Nichols

Avani A. Pendse, Ph.D.

Dissertation title: Peroxisome Proliferator Activated Receptor-gamma P465L Point Mutation in Diabetes and Atherosclerosis
Advisor: Nobuyo Maeda

Chih-Hong Wang, Ph.D.
Dissertation title: Inhibition of Renin Angiotensin System Improves Leptin and Insulin Sensitivity, but Impairs Erythropoiesis in Bone Marrow via Thyroid Hormone
Advisor: Nobuyuki Takahashi

2009

Diane E. Bender, Ph.D.
Dissertation title: Characterization of a Feline Model of Factor XII Deficiency: The In Vivo Role of FXII in Vascular Injury and Inflammatory Responses
Advisor: Dwight A. Bellinger

Robert A. Campbell, Ph.D.
Dissertation title: The Role of Different Vascular Cells in Fibrin Clot Formation and Structure
Advisor: Alisa S. Wolberg

Jennifer C. Carter, Ph.D.
Dissertation title: PPAR-gamma Ligands and Adipocytes Regulate Expression of the Plasminogen Activator System in Breast Cancer
Advisor: Frank C. Church

Kathleen R. Nevis, Ph.D.
Dissertation title: Molecular Characterization of a Replication Licensing Checkpoint
Advisor: Marila Cordeiro-Stone and Jeanette G. Cook

Christopher M. Scull, Ph.D.
Dissertation title: The Role of Platelet-Macrophage Interactions in Inflammation and Wound Healing
Advisor: Thomas H. Fischer

Dean P. Staus, Ph.D.
Dissertation title: Regulation of Smooth Muscle Specific Gene Transcription by the Diaphanous-Related Formins
Advisor: Christopher P. Mack

Xuebin Yang, Ph.D.
Dissertation title: Molecular and Cellular Mediators in Radiation-Induced Lung Injury
Advisor: Suzanne L. Kirby

2008

Jeremiah S. Hinson, Ph.D.
The Regulation of Myocardin Factor-Dependent Transcription in Vascular Smooth Muscle
Advisor: Christopher P. Mack

Lee E. Mangiante, M.S.
Dissertation title: The Role of Focal Adhesion Kinase in Vascular Smooth Muscle Cell Migration
Advisor: Joan M. Taylor

Hind E. Muallem, Ph.D.
Dissertation title: Association of Genetic Variations in the 3’UTR of the Human Low Density Lipoprotein Receptor with the Lipid Parameters in the Atherosclerosis Risk in Communities (ARIC) Study
Advisor: Nobuyo Maeda

Liliana A. Ponguta, Ph.D.
Dissertation title: Androgen Receptor and Epidermal Growth Factor Signaling in Prostate Cancer
Advisor: Elizabeth M. Wilson

Jill C. Rau, Ph.D.
Dissertation title: Engineering of Serpins for Vascular Application
Advisor: Frank C. Church

Jacqueline Risher Roll, Ph.D.
Dissertation title: Mechanism and Consequence of the Hypermethylator Phenotype in Human Breast Cancer
Advisor: William B. Coleman

Kristen King White, M.S.
Thesis title: Investigation of a Novel +ACA BRCA1 Promoter Polymorphism and Its Impact on the Breast Cancer Susceptibility Phenotype
Advisor: William B. Coleman

2007

Michael Altenburg, Ph.D.
Dissertation title: Atherosclerotic Mechanisms of Apolipoprotein E Isoforms

Advisor: Nobuyo Maeda

Joshua M. Astern, Ph.D.
Dissertation title: Myeloperoxidase in Vascular Disease and Autoimmunity
Advisor: Ronald J. Falk

Lea M. Beaulieu, Ph.D.
Dissertation title: Role of the Protein C System in Breast Cancer Cell Invasion and Endothelial Cell Angiogenesis
Advisor: Frank C. Church

D. Hunter Best, Ph.D.
Dissertation title: Liver Regeneration by Small Hepatocyte-like Progenitor Cells After Hepatotoxic and Necrotic Injury in Fischer 344 Rats
Advisor: William B. Coleman

Jessica N. DelBove, Ph.D.
Dissertation title: Characterization of the Tumor Suppressor Capabilities of SWI/SNF Complex Member BAF155 in Cancer Cell Lines and Cooperation of SNF5 and p53 Pathways
Advisor: Bernard E. Weissman

Laura A. DiMichele, Ph.D.
Dissertation title: Focal Adhesion Kinase in Cardiac Development and Disease
Advisor: Joan M. Taylor

Jennifer Bushman Gilner, Ph.D.
Dissertation title: Enrichment of Therapeutic Hematopoietic Stem Cell Populations From Embryonic Stem Cells
Advisor: Suzanne Kirby

Jennifer E. Jahn, Ph.D.
Dissertation title: Identification of Synaptotagmin XIII as a Liver Tumor Suppressor Gene
Advisor: William B. Coleman

Terrence D. Lewis, Ph.D.
Dissertation title: Mechanisms of Estrogen Sensitivity in the Human Endometrium
Advisor: David G. Kaufman

Liisa Sundberg Smith, Ph.D.
Dissertation title: A Role for Focal Adhesion Kinase in Vascular Smooth Muscle Cell Proliferation, Migration, and Differentiation
Advisor: Joan M. Taylor

2005



Jingjing Chai, Ph.D.
Dissertation title: Identification of the Signal Transduction Pathway and Functional Domains of hSNF5 in Human Rhabdoid Tumor Cell Line and Mouse Rhabdoid Tumors
Advisor: Bernard E. Weissman

Danny R. Gray, Ph.D.
Dissertation title: Effects of Androgen Deprivation on the Human Prostate Microenvironment
Advisor: Gary J. Smith

Timothy P. Heffernan, Ph.D.
Dissertation title: Mechanisms of S Checkpoint Function in Human Cells
Advisor: William K. Kaufmann

Charlotte A. Lanteri, Ph.D.
Dissertation title: Mechanisms of Uptake and Action of DB75 [2,5-bis(4-amidinophenyl)furan] in African Trypanosomes
Advisor: Richard R. Tidwell

Julie L. Ryan, Ph.D.
Dissertation title: Prevalence of Epstein-Barr Virus in Gastric Mucosa and Influences on Selected Gene Expression in Gastric Carcinoma
Advisor: Margaret L. Gulley

Lisa Marie Sturk, Ph.D.
Dissertation title: Comparative Pharmacokinetics of DB289 and DB844: Investigating Improved Prodrug Efficacy Against Mouse Models of Sleeping Sickness
Advisor: Richard R. Tidwell

Yau-Sheng Tsai, Ph.D.
Dissertation title: Peroxisome Proliferator-Activated Receptor Gamma in the Metabolic Syndrome
Advisor: Nobuyo Maeda

2004

Brandi Whitley Hilder, Ph.D.
Dissertation title: Plasminogen Activator Inhibitor-1 in Breast and Ovarian Cancer Invasion
Advisor: Frank C. Church

2003

Susan D. Hester, Ph.D.
Dissertation title: Genetic Events Involved in Formaldehyde-induced Carcinogenesis
Advisor: Douglas C. Wolf


William F. Pendergraft III, Ph.D.
Dissertation title: In Depth Analysis of the Myeloid Protease, Proteinase 3, as an Autoantigen and a Mediator of Vascular Injury
Advisor: Ronald J. Falk

2002

Bryan L. Betz, Ph.D.
Dissertation title: The hSNF5/INI1 Tumor Suppressor Gene: Mutational Analysis and Functional Characterization
Advisor: Bernard E. Weissman


Sharon Ricketts Betz, Ph.D.
Dissertation title: Identification and Characterization of Candidate Liver Tumor Suppressor Genes from Human Chromosome 11p11.2-p12
Advisor: William B. Coleman


Paula B.Deming, Ph.D.
Dissertation title: Mechanisms of Human Decatenation Checkpoint Function
Advisor: William K. Kaufmann


Jeffrey B. Hodgin, Ph.D., M.D.
Dissertation title: Molecular Mechanisms of Atheroprotection by 17b-estradiol
Advisor: Nobuyo N. Maeda


Nazumi Alice S. Yamada, Ph.D.
Dissertation title: Microsatellite Instability in the Absence of Mismatch Repair Defects
Advisor: Rosann A. Farber


Suzanne T. Newberry, M.S.
Thesis title: Methylation-dependent Epigenetic Silencing of BRCA1 in Sporadic Breast Cancer
Advisor: William B. Coleman


2001

Kelly A. Hogan, Ph.D.
Dissertation title: Fibrinogen Vlissingen/Frankfurt IV: Studies with Recombinant Fibrinogen and Gene-Targeted Mice
Advisor: Susan T. Lord


Jennifer Wemhoff Mitchell, Ph.D.

Dissertation title: Structure, Function, and Physiological Role of Heparin Cofactor II
Advisor: Frank C. Church


Dorothy H. Wood, Ph.D.
Dissertation title: The Role of Imidazoline Receptors in 1,5-Bis(4-Amidinophenoxy) Pentane (Pentamidine) Toxicity
Advisor: Richard R. Tidwell


Alexis T. Henry, M.S.
Thesis title: Characterization of Single Nucleotide Polymorphisms (SNPs) in Protein C Inhibitor
Advisor: Frank C. Church

2000

Mohammed BaSalamah, Ph.D.
Dissertation title: Testican: Novel Human Gene Product
Advisor: Cora-Jean S. Edgell


Cheryl A. Cistulli, Ph.D.
Dissertation title: Cell Cycle Checkpoints and Human Carcinogenesis
Advisor: William K. Kaufmann


Gavin J. Gordon, Ph.D.
Dissertation title: Characterization of the Cellular Responses During Liver Regeneration in Retrorsine-exposed Rats and Identification of a Novel Hepatic Progenitor Cell
Advisor: William B. Coleman


Tara N. Lyons-Darden, Ph.D.
Dissertation title: The Role of DNA Instability in Triplet Repeat Expansion During in vitro DNA Replication
Advisor: Michael D. Topal


Diane Palmieri, Ph.D.
Dissertation title: Serpins in Cancer
Advisor: Frank C. Church


Arti C. Patel, Ph.D.
Dissertation title: Analysis of Candidate Suseceptability Genes and the Role of DNA Methylation in Mouse Lung Carcinogenesis
Advisors: J. Carl Barrett and Theodora R. Devereux


Arlene S. Pereira, Ph.D.
Dissertation title: A Study of Antiretroviral Drug Penetration into the Male Genital Tract Using High Performance Liquid Chromatography and Tandem Mass Spectrometry
Advisor: Richard R. Tidwell


Kelly L. Price, M.S.
Dissertation title: Genetic Instability in Cervical Carcinogenesis
Advisor: William K. Kaufmann


Michelle A. Rider, M.S.
Thesis title: Suppression of Tumorigenicity in Rat Liver Tumor Cells by Human Chromosome 13: Evidence Against the Involvement of pRb
Advisor: William B. Coleman


1999

Susannah Jo Bauman, Ph.D.
Dissertation title: Antithrombotic Properties of Heparin Cofactor II
Advisor: Frank C. Church


Sharon King Bullock, Ph.D.
Dissertation title: UV-Induced Inhibition of DNA Replication
Advisor: Marila Cordeiro-Stone


Tracey Dawson Cruz, Ph.D.
Dissertation title: Chemokine Receptors in Inflammatory Disease: Studies Using Chemokine Receptor Knockout Mice
Advisor: Nobuyo N. Maeda


Vincent R. Torti, Ph.D.
Dissertation title: Cellular Aging in Endometrial Stromal Cells Promotes the Growth of Immortalized and Carcinoma-derived Endometrial Epithelial Cells via Paracrine Interactions: The Role of Interleukin-1a and Interleukin-1b
Advisor: David G. Kaufman


Cynthia Irvin Behe, M.S.
Thesis title: Defective Cell Cycle Checkpoint Function in Transformed Hepatocytes and WB-F344 Hepatic Epithelial Stem-like Cells
Advisor: William K. Kaufmann

1998

Julia T. Arnold, Ph.D.
Dissertation title: Human Endometrial Stromal Cells Regulate Epithelial Cell Growth and Function In Vitro
Advisor: David G. Kaufman


Shyra J. Crider-Miller, Ph.D.
Dissertation title: Identification of Candidate Pediatric Tumor Suppressor Genes on Human Chromosome 11p15.5
Advisor: Bernard E. Weissman


Hitendra S. Jethwa, Ph.D.
Dissertation title: Molecular Characterization of the Spontaneous Anti-Myeloperoxidase Antibody Response in SCG/Kj Mice
Advisor: J. Charles Jennette


Donald W. Lawrence, Jr., Ph.D.
Dissertation title: The Regulation of Human Neutrophil Adhesion and Spreading by 3',5'-cyclic Guanosine Monophosphate
Advisor: Katherine B. Pryzwansky


Jonathan M. Phillips, Ph.D.
Dissertation title: The Association of Specific DNA Sequences with the Nuclear Matrix During G0 and S Phases of the Cell Cycle
Advisor: David G. Kaufman


1997

Laura L. (Neese) Glasscock, Ph.D.
Dissertation title: Protein C Inhibitor: Structure-Activity Relationships and Pathobiological Aspects
Advisor: Frank C. Church


Paula M. Oliver, Ph.D.
Dissertation title:Targeted Gene Titration of the Natriuretic Peptide Receptor A to Study Its Role in Essential Hypertension
Advisor: Nobuyo N. Maeda


Karen K. Phillips, Ph.D.
Dissertation title: Identifying Suppressor Genes for Breast Cancer and Wilms Tumor
Advisor: Bernard E. Weissman

1995

Delores J. Grant, Ph.D.
Dissertation title: Expression of the Haptoglobin Gene Complex
Advisor: Nobuyo N. Maeda


Steven C. Hoffman, M.S.
Thesis title: Altered Expression of the p53 Tumor Suppressor Gene Enhances the Tumorigenic Potential of Neoplastically Transformed WB-F344 Rat Liver Epithelial Cells
Advisor: Gary J. Smith


Lara K. Surles, M.S.
Thesis title: The Paradoxical Effects of Lovastatin, an HMGCoA Reductase Inhibitor, on Apolipoprotein E Deficient Mice
Advisor: Nobuyo N. Maeda


1994

Chia Chiao, Ph.D.
Dissertation title: Mechanisms of Promotion of Hepatocarcinogenesis in vitro
Advisor: William K. Kaufmann


Suzanne L. Kirby, M.D., Ph.D.
Dissertation title: Bone Marrow Stromal Proteoglycans and Their Roles in Hematopoiesis
Advisor: Stuart A. Bentley


Rebecca A. Shirk, Ph.D.
Dissertation title:Structure-Function Studies of Heparin Binding Serpins
Advisor: Frank C. Church


Sunny H. Zhang, Ph.D.
Dissertation title:An Animal Model of Atherosclerosis: The Apolipoprotein E Deficient Mice
Advisor: Nobuyo N. Maeda


Adella R. Clark, M.S.
Thesis title: Immunogenetics of Inhibitor Response to FVIII:C
Advisor: Howard M. Reisner


Margaret M. Doherty, M.S.
Thesis title: Regulation of the Epidermal Growth Factor Receptor in Rat Tracheal Epithelial Cells
Advisor: Paul Nettesheim


Julia K. Holtz, M.S.
Thesis title: Defining the Functional Domains of the NaeI Restriction Endonuclease by Random Mutagenesis
Advisor: Michael D. Topal


1993

Terry L. Blakenship-Paris, D.V.M.,Ph.D.
Dissertation title:Clostridium difficile Enterocolitis Associated With an Atherogenic, High Fat Diet in Hamsters
Advisor: Jerjang Chang


Leah D. Fletcher, Ph.D.
Dissertation title: Cloning and Characterization of Rat Derived Pneumocystis carinii Genes
Advisor: Christine C. Dykstra


Phillip (Andy) Futreal, Ph.D.
Dissertation title: Physical Mapping of Tumor Suppressor Genes on Human Chromosomes 1q and 17q
Advisor: J. Carl Barrett


Debra K. McMahon, Ph.D.
Dissertation title: Characterization of a Two Motif Isoform of the Dihydropyridine Receptor in Skeletal Muscle
Advisor: Nadia N. Malouf


Kimberly Weiss Schuenke, Ph.D.
Dissertation title: Analysis of a Novel Protein Antigen Gene of Rickettsia Conorii
Advisor: David H. Walker

1992

Pengchin Chen, Ph.D.
Dissertation title: Mapping of Tumor Suppressor Genes in Soft Tissue Sarcoma Cell Lines by Functional Analyses
Advisor: Bernard E. Weismann


Dean M. McCord, Ph.D.
Dissertation title: Structure-Function Relationships in Human Coagulation Factor IX
Advisor: Harold R. Roberts


Joan P. Packenham, Ph.D.
Dissertation title: Effect of Estradiol on Von Willebrand Factor Expression in Cultured Endothelial Cells
Advisor: Cora-Jean S. Edgell


Herbert C. Whinna, M.D., Ph.D.
Dissertation title: Structure Function Studies on Heparin Cofactor II
Advisor: Frank C. Church


Todd A. Wyatt, Ph.D.
Dissertation title: Neutrophil cGMP-Dependent Protein Kinase: Its Identification and Response to Formyl-Peptide and Calcium Ionophore
Advisor: Katherine B. Pryzwansky


Shelley L. Hoogstraten-Miller, D.V.M., M.S.
Thesis title: Von Willebrand Factor in Plasma, Platelets, and Selected Tissues of Ferrets
Advisor: Dwight Bellinger


1991

Linda A. Charles, Ph.D.
Dissertation title: The Reactivity and Pathogenicity of Anti-Neutrophil Cytoplasmic Autoantibodies
Advisor: J. Charles Jennette


Daniel S. Marsman, Ph.D.
Dissertation title: Peroxisome Proliferator Hepatocarcinogenesis in Rats: The Role of Cell Replication in Tumor Development
Advisor: James A. Popp


Ying Li, M.S.
Thesis title: Repair of BPDE-DNA in Human Fibroblasts
Advisor: William K. Kaufmann


Thomas H. Rude, M.S.
Thesis title: Cloning and Sequencing of the Cryptococcus neoformans NAD-dependent Mannitol Dehydrogenase Gene
Advisor: Christine C. Dykstra



1990

Richard D. McFarland, Ph.D.
Dissertation title: Mutagenesis in the Lambda Immunoglobulin Gene in a Human Lymphoblastoid Cell Strain
Advisor: Gary J. Smith


Linda L. Barrett, M.S.
Thesis title: Five-Azacytidine Treatment Increases Anchorage Independent Growth of Human Endometrial Stromal Cells Expressing SV40 Large T Antigen
Advisor: David G. Kaufman


1989

Mark Gregory Bolyard, Ph.D.
Dissertation title: Characterization of Subunits of Human Fibrinogen Expressed in Escherichia coli
Advisor: Susan T. Lord


Richard James Rahija, Ph.D.
Dissertation title: Factors Influencing the Initiation by Anti(+)benzo(a)pyrenediol-expoxide of Hepatocarcinogesis in the Male F344 Rat
Advisor: David G. Kaufman


Jo Ann Tyndall, M.S.
Thesis title: Azurophil and Specific Granule Exocytosis by N-formyl-methionyl-leucyl-phenylalanine-stimulated Human Neutrophils
Advisor: Katherine B. Pryzwansky


1988

John James Dino, Jr., Ph.D.
Dissertation title: Characterization of Radioactive "Early-eluting" Chromatographic Material Resulting from Interactions of Tritiated Benzo[a]pyrene With Liver Nucleic Acids in A/HeJ Female Mice
Advisor: David G. Kaufman


Brian G. Short, Ph.D.
Dissertation title: Effects of Unleaded Gasoline on Renal Tubular Cell Kinetics and Tumor Promotion in Rats
Advisor: James A. Swenberg


Roc Bauman, M.S.
Thesis title: Atherosclerosis in Hypercholesteerolemic Normal and von Willenrand's Disease Swine
Advisor: Thomas R. Griggs


Russell C. Cattley, M.S., V.M.D., Ph.D.
Thesis title: Peroxisome Proliferator Hepatocarcinogenesis in Rats
Advisor: James A. Popp


Romas Agu Vaitkus, M.S.
Thesis title: Transformation of Human Endometrial Stromal Cells With a Temperature-sensitive, Origin-minus, SV40 Recombinant Plasmid
Advisor: David G. Kaufman


1987

Mark de Serres, M.S.
Thesis title: A Monoclonal Antibody Whose Binding is Inhibited by Divalent Cations
Advisor: Howard M. Reisner


Richard John Russell Lombardy, M.S.
Thesis title: Computer-assisted Molecular Modeling Studies of Potent Amidine Inhibitors Bound to the Active Site of Trypsin
Advisor: Richard R. Tidwell


1986

Norman A. Doggett, Ph.D.
Dissertation title: The Temporal Order of Replication of Protooncogenes in Synchronized C3H 10T1/2 Cells
Advisor: David G. Kaufman


Jeffrey Bruce Garris, M.S.

Thesis title: Purified Human Factor VIII Procoagulant Protein: Comparative Hemostatic Response After Infusions into Hemophilic and von Willebrand Disease Dogs
Advisor: Kenneth M. Brinkhous


1985

Karen Louise S. Bentley, Ph.D.
Dissertation title: Cell Cycle-related Genotoxic Effects of 4-Nitroquinoline-1-oxide in C3H 10T1/2 Cells
Advisor: Joe W. Grisham


Yung Sheng Eric Wang, Ph.D.
Dissertation title: Plasma Free Fatty Acids: Development and Clinical Application of a New Analytical Method
Advisor: William W. McLendon


Michel G. Haddad, M.S.
Thesis title: Idiotpy and Factor VIII Inhibitors: Towards the Production of a Monoclonal Anti-Idiotypic Antibody
Advisor: Howard M. Reisner


Otis Speight, M.S.
Thesis title: Pathogenesis of Murine Infection Wtih Parainfluenza Virus in Mice: A Natural Paramyxovirus-Host Relationship
Advisor: David H. Walker


1984

Tessie Brown McNeely, Ph.D.
Dissertation title: Heparin: A Theory on Its In Vitro Anticoagulant Mechanism of Action
Advisor: Michael J. Griffith


Richard S. Paules, Ph.D.
Dissertation title: An Investigation of the Effects of Exposure to a Chemical Carcinogen on DNA Replication in Mammalian Cells Utilizing Quantitative EM Visualization of Antibodies Bound to Carcinogen-DNA
Advisor: David G. Kaufman


Bharat R. Gandhi, M.S.
Thesis title: Production of Monoclonal Antibodies and Their Use in Characterization of Antigenic Proteins of Toxoplasma gondii Tachyzoites
Advisor: G. Yancey Gillespie


1983

Samy Samuel Iskandar, M.D., Ph.D.
Dissertation title: The Pathogenesis of Heterologous Protein-induced Glomerulonephritis: Studies in Inbred Mouse Strains
Advisor: J. Charles Jennette


James V. Lange, Ph.D.
Dissertation title: Rickettsial Studies: Isolation and Quantitation of Rickettsiae in Patients With Rocky Mountain Spotted Fever and Production of Monoclonal Antibodies to Rickettsia rickettsii
Advisor: David H. Walker


Marjorie S. Read, Ph.D.
Dissertation title: Venom Coagglutinin (VCA). The Platelet Aggregating Principle of Bothrops Venoms: Von Willibrand Factor-dependent Platelet Aggregation
Advisor: Kenneth M. Brinkhous

1982

Arthur Palfrey Bode, Ph.D.
Dissertation title: Platelet Factor One in Human Platelets
Advisor: Fred Dombrose


Bruce Hugh Dorman, Jr., Ph.D.
Dissertation title: Chemical Carcinogen Effects on Human Endometrium In Vitro: Phenotypic Alterations in Cell Cultures and Carcinogen Binding to DNA in organ Cultures
Advisor: David G. Kaufman


Mary S. Baker, M.S.
Thesis title: Alkylation of Deoxyribonucleotides and Their Role in Mutagenesis
Advisor: Michael D. Topal


1981

Mary Ann Pregnall Lamb, Ph.D.
Dissertation title: Immunochemical Studies on the Multimeric Structure of Factor VIII Related Antigen
Advisor: Robert H. Wagner


Gerald William Upton, D.D.S., M.S., Ph.D.
Dissertation title: Platelet Inhibition and Thrombosis in the Pathogenesis of Bacterial Diseases
Advisor: Frederic G. Dalldorf


William Patrick Bennett, M.S.
Thesis title: The Effects of an Extracellular Protease From Serratia marcescens on Membrane Functions of Human Platelets
Advisor: Herbert A. Cooper


1980

Richard M. Lewis, Ph.D.
Dissertation title: Studies on the Binding of Human Anti-Factor IX Antibodies to Factor IX Protein
Advisor: Howard M. Reisner


Marc J. Mass, Ph.D.
Dissertation title: Species Differences in the Activation of a Carcinogen in Respiratory Epithelium: A Possible Explanation for the Unequal Susceptibilities of Tracheal Epithelium of Rats and Hamsters to Carcinogenesis by Benzo(a)pyrene
Advisor: David G. Kaufman


Michael S. Owens, Ph.D.
Dissertation title: Marijuana Use Among Drivers in Fatal Single-vehicle Accidents
Advisor: Arthur McBay


1979

Ronald Kent Charlton, Ph.D.
Dissertation title: An Investigation of the Loss of Cytochrome P-450 From Cultured Hepatocytes
Advisor: Joe W. Grisham


William K. Kaufmann, Ph.D.
Dissertation title: Studies of the Susceptibility of Hepatocytes in Specific Cell Cycle States to Carcinogenesis by N-Methyl-N-Nitrosourea
Advisor: David G. Kaufman

1978

Fernando A. Santos, M.D., Ph.D.
Dissertation title: Purification and Characterization of Bovine Platelet Aggregating Factor (PAF): I: Purification of PAF. II: Immunological Characterization of PAF.
Advisor: Robert H. Wagner


Christine Norma Vogel, Ph.D.
Dissertation title: In Vivo and In Vitro Biology of Antithrombin III and Thrombin
Advisor: Roger L. Lundblad


1975

James Christian Lamb IV, J.D., Ph.D.
Dissertation title: 1951-New Factors in the Regulation of Exocrine Pancreatic Secretion in the Rat
Advisor: J.D. Geratz


David Edward Sharp, M.D., Ph.D.
Dissertation title: 1945-Morphologic Studies on Blood Platelet Response to Adenosine Diphosphate and Its Modification InVivo and In Vitro
Advisor: Mason


Sheryl Kathrein, M.S.
Thesis title: A Comparison of Cryoprecipitate Yeilds by Different Methods
Advisor: James E.T. Laningham


Kenneth M. Lovette, M.S.
Thesis title: The Subcellular Distribution and Partial Characteerization of Cholinesterase Activities in Canin Platelets
Advisor: Hanson Chuang


B. Alston Macon, Jr., M.S.
Thesis title: Calcium Induced Conformational Changes in the Amino Acid Terminal End of Prothrombin
Advisor: Koehler


Gilbert C. White, M.D., M.S.
Thesis title: The Effect of Various Anticoagulants on the Adhesiveness of Blood Platelets and Studies on the Mechanism of Platelet Adhesion.
Advisor: Kenneth M. Brinkhous


1974

Daniel L. Leonard, M.S.
Thesis title: Measurements of Chromium in Hair and Soft Tissue Using Flameless Atomic Absorption (FAA) Spectroscopy
Advisor: Robert A. Goyer


Daniel L. Leonard, M.S.
Thesis title: Metabolic Effects of Oral NTA and Equivalent Injection Dose Administration of NTA and EDTA in the Adult Rat
Advisor: Robert A. Goyer


Larry Paul Thornburg, L.P., D.V.M., M.S.
Thesis title: Direct Enzyme Cytochemical Investigation of the Trigeminal Ganglion of C57BL/6J-dtj Mice and Their Littermates With an Hereditary Sensory Neuropathy (Dystonia Musculorum)
Advisor: Stowe/Hanker


1972

Dolph Oliver Adams, M.D., Ph.D.
Dissertation title: The Differentiation of Mononuclear Phagocytes In Vivo: A Correlated Histologic and Fine Structural Study
Advisor: Kenneth M. Brinkhous


1971

Waykin Nopanitaya, Ph.D.
Thesis title: Effects of the Pungent Principle of Hot Red Pepper (Capsaicin) in Combination With Diets of Varying Protein Content on the Duodenal Absorptive Cells and the Growth of the Rat
Advisor: Sylvanus W. Nye


George Peter Wysocki, D.D.S., Ph.D.
Dissertation title: Synovial Membrane Changes in Hemophilic Arthopathy: A Light, Transmission and Scanning Electron Microscope Study
Advisor: Kenneth M. Brinkhous


Douglas Edward Mooreside, M.D., M.S.
Thesis title: The Effects of Adenine on the Clotting Factors in Fresh Blood, Stored Blood, and Stored Fresh Frozen Plasma
Advisor: James E.T. Laningham


Robert L. Reddick, M.D., M.S.
Thesis title: Thrombocytopenia of Hibernation: With Special Reference to the Role of the Spleen.
Advisor: Penick


1970

Joe Paul Hurt, M.D., M.S., Ph.D.
Dissertation title: Dynamics of Diffuse Introvascular Coagulation Associated With an Experimental Glioma
Advisor: Krigman


Hussian Ismail Saba, M.D., Ph.D.
Dissertation title: Effects of Polymorphonuclear Leukocytes on Blood Coagulation and Fibrinolysis
Advisor: Harold R. Roberts


Paul deVendel Davis, J.D., M.S.
Thesis title: The Heterozygote for Hemophilia A and B: A Coagulation and Genetic Study
Advisor: Kenneth M. Brinkhous


1969

Theodore Hyde Kiesselbach, M.D., Ph.D.
Dissertation title: Coagulation Factor XIII: A Thrombin-labile Protein in Plasma, Platelets, and Bone Marrow Megakaryocytes
Advisor: Robert H. Wagner


Mohammad A. Nadjem, M.D., M.S.
Thesis title: A Study of the Anatomical Pathology of Liver Fluke Infestation (Opisthorchis viverrini) in Thai
Advisor: Sylvanus W. Nye


1968

William Phillip Webster, D.D.S., M.S.
Thesis title: Studies of In Vivo and Ex Vivo Release of Factor VIII From Organs and Tissues
Advisor: Penick


1967

Roy Vernon Land, M.D., M.S.
Thesis title: A Study of Some Effects of E. coli Endotoxin on Rabbit Blood Platelets
Advisor: Kenneth M. Brinkhous


William Dumas McLester, M.D., Ph.D.
Dissertation title: Studies on Circulating Anticoagulants in Classical Hemophilia and Christmas Disease
Advisor: Robert H. Wagner


1965

Ernesto A. deVeyra, Jr., M.D., M.S.
Thesis title: Nerve Fiber Lesions in the Brain Stem Following Head Injury
Advisor: Margaret C. Swanton


Joe Paul Hurt, M.D., M.S.
Thesis title: Further Purification of Beta Alanine Precipitated Human Antihemophilic Factor (AHF) by Adsorption or Reprecipitation
Advisor: Robert H. Wagner


1964

Reginald Gladstone Mason, M.D., M.S.
Thesis title: 1933-Studies on the Platelet Agglutinating Activity of Recalcified Normal and Pathologic Human Plasmas
Advisor: Kenneth M. Brinkhous


1959

Perry F. Harris, M.D., D.V.M., M.S.
Thesis title: Hemophilic Heterozygotes: A Reevaluation of the Concentration of Antihemophilic Factor in Their Plasma
Advisor: Robert H. Wagner


1958

E. Carwile LeRoy, M.D., M.S.
Thesis title: 1933-Historical and Experimental Studies of the Spontaneous Agglutination of Mammalian Blood Platelets
Advisor: Kenneth M. Brinkhous


1957

Robert A. Farrell, M.D., M.S.
Thesis title: A Study of Some Tosyl-Arginine and Acetyl-Tyrosine Esterases and Their Relationship to the Coagulation of Blood
Advisor: Robert H. Wagner


1954

George Elton Cox, M.D., M.S.
Thesis title: Cholesterol in Atheroschlerosis: Studies on its Biosynthesis
Advisor: C. Bruce Taylor

 

Molecular and Cellular Pathology Graduate Program