Antonio L. Amelio

Antonio L. Amelio

Assistant Professor
UNC School of Dentistry 

Lineberger Comprehensive Cancer Center

385 South Columbia Street
3605 Koury Oral Health Sciences
Chapel Hill, NC 27599
919-537-3309


Education

2005 - PhD in Molecular Genetics & Microbiology, University of Florida

Research Interests
Dr. Amelio’s lab recently developed novel LumiFluor® optical reporters and is implementing these reporters for the non-invasive, high resolutionin vivo optical imaging of tumor development, progression, and response to therapeutic intervention.

Publications

  1. Schaub FX, Reza MS, Flaveny CA, Li W, Musicant AM, Hoxha S, Guo M, Cleveland JL, Amelio AL. (2015). Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis. Cancer Research. [Epub ahead of print]
  2. Peña CG, Nakada Y, Saatcioglu HD, Aloisio GM, Cuevas I, Zhang S, Miller DS, Lea JS, Wong KK, DeBerardinis RJ, Amelio AL, Brekken RA, Castrillon DH. (2015). LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment. Journal of Clinical Investigation. [Epub ahead of print] 
  3. Flaveny CA, Griffett K, El-Gendy Bel-D, Kazantzis M, Sengupta M, Amelio AL, Chatterjee A, Walker J, Solt LA, Kamenecka TM, Burris TP. ( 2015). Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis. Cancer Cell, 28(1), 42-56. 
  4. Fallahi M, Amelio AL, Cleaveland JL, Rounbehler RJ. (2014). CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin. PLos One, 9(12): e115517.
  5. Cao C, Gao R, Zhang M, Amelio AL, Fallahi M, Chen Z, Gu Y, Hu C, Welsh EA, Engel BE, Haura EB, Cress WD, Wu L, Zajac-Kaye M, Kaye FJ. Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer. Journal of the National Cancer Institute, 107(1): 358