Education and Training
State University of NY College at New Paltz, BS, 1979
Johns Hopkins University, PhD, 1985
Areas of Interest
Airway epithelial cell biology: stem cells, innate immunity, cystic fibrosis
My laboratory research is focused on basic cell biology questions as they apply to clinical lung disease problems. Our main work recently has been contributing to the NIH NHLBI Lung Repair and Regeneration Consortium, in which we are examining factors regulating airway and distal lung epithelial growth and differentiation, with a focus on regulation of stemness and differentiation of the key epithelial cell types. I contribute to UNC team science efforts on cystic fibrosis and aerodigestive cancers and direct a highly respected tissue procurement and cell culture Core providing primary human lung cells and other resources locally, nationally and internationally. I am the inaugural co-director of the Respiratory Block and am the “Physiology Coil” in the new UNC Translational Educational Curriculum for medical students and also teach in several graduate level courses.