Boosting immune system T cells to effectively attack solid tumors, such as breast cancers, can be done by adding a small molecule to a treatment procedure called chimeric antigen receptor-T (CAR-T) cell therapy, according to a study by researchers at the UNC Lineberger Comprehensive Cancer Center. The boost helps recruit more immune cells into battle … Continued

Calina Copos, PhD Dr. Copos arrived at UNC from the Courant Institute for Mathematical Sciences at New York University. She is a mathematical biologist who uses computational tools to reveal mechanisms in cell biology. She develops mechanical and biochemical theoretical models of single and collective cell migration and self-organization inside cells. These interests are motivated … Continued

There is an urgent need for a vaccine with efficacy against SARS-CoV-2. We hypothesize that peptide vaccines containing epitope regions optimized for concurrent B cell, CD4+ T cell, and CD8+ T cell stimulation would drive both humoral and cellular immunity with high specificity, potentially avoiding undesired effects such as antibody-dependent enhancement (ADE)

Christoph Rau, PhD My research focuses on using model organism populations to study cardiovascular disease.  I obtained my PhD in Microbiology, Immunology and Molecular Genetics at UCLA, where I began working with the Hybrid Mouse Diversity Panel to study the genetics underlying heart failure.  In my postdoc, I expanded into studying the epigenome and developing … Continued

A multidisciplinary team led by Dr. Mark Zylka shows that deletion of TOP1, an enzyme that relieves DNA stress during transcription, in neurons causes genomic instability and early onset of neurodegeneration. Read this exciting work in Nature  

Researchers led by Blossom Damania, PhD, reported that Kaposi sarcoma-associated herpesvirus, a virus linked to three human cancers, uses a protein produced by its human host to come out of hiding and reactivate.

Jonathan Serody, MD, director of UNC’s Bone Marrow Transplantation & Cellular Therapy Program, is the new division chief for hematology. Ethan Basch, MD, the Richard M. Goldberg Distinguished Professor in Medical Oncology, is the new division chief for oncology. Both are members of the UNC Lineberger Comprehensive Cancer Center. More

Christoph Rau, PhD My research focuses on using model organism populations to study cardiovascular disease.  I obtained my PhD in Microbiology, Immunology and Molecular Genetics at UCLA, where I began working with the Hybrid Mouse Diversity Panel to study the genetics underlying heart failure.  In my postdoc, I expanded into studying the epigenome and developing … Continued

I have joined the faculty of the Department of Pharmacology and Computational Medicine Program at UNC Chapel Hill. Previously I was a postdoctoral fellow with Peter K. Sorger at Harvard Medical School’s Laboratory of Systems Pharmacology and Department of Systems Biology, where I applied experiments and computation to understand the mechanisms of combinations of cancer … Continued

December 19, 2019 Lisa A. Carey, MD, FASCO The American Society of Clinical Oncology has elected UNC Lineberger Comprehensive Cancer Center’s Lisa A. Carey, MD, FASCO, to its Board of Directors. She will begin her four-year term during ASCO’s annual meeting in June 2020.