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Vincent Lab discovers six immune subtypes of cancer

April 8, 2019

Benjamin Vincent, MD, Assistant Professor in the School of Medicine (Hematology/Oncology) and his lab have performed a comprehensive genomics evaluation of the tumor immune microenvironment in The Cancer Genome Atlas dataset, discovering six immune subtypes of cancer. These and other findings are associated with survival and are being developed as biomarkers of immunotherapy response in multiple tumor … Read more

Guorong Wu lab develops computational tools to understand brain function

April 8, 2019

Guorong Wu, PhD, and his lab are interested in developing cutting-edge computational tools to understand the brain, using state-of-the-art neuroimaging, genetics, and machine-learning technologies. With this in mind, they work to discover biomarkers of neurodegenerative diseases, characterize genetic influences on brain structure, and create personalized diagnostic engines.

Scientists train a computer to classify breast cancer tumors

December 7, 2018

In a study published in the journal NPJ Breast Cancer, Charles M. Perou, PhD, Melissa Troester, PhD, graduate student Heather D. Couture and colleagues reported they used a form of artificial intelligence to train a computer to identify certain features of breast cancer tumors from images. UNC Lineberger’s Charles M. Perou, PhD, and Melissa Troester, … Read more

Featured Faculty: Jeremy Purvis, PhD

September 26, 2018

Jeremy Purvis is an Assistant Professor of Genetics and Cancer Cell Biology. His work is focused on signal transduction in single human cells, specifically interested in why genetically identical cells choose different fates and how these decisions are influenced by the cellular environment. His lab uses a variety of experimental and theoretical approaches including transcriptional … Read more

Regina Barzilay, PhD

September 17, 2018

UNC Computational Medicine Program presenting inaugural seminar speaker, Regina Barzilay, PhD. Dr. Barzilay is a Delta Electronics professor in the Department of Electrical Engineering and Computer Science and a member of the Computer Science and Artificial Intelligence Laboratory at the Massachusetts Institute of Technology. Her research interests are in natural language processing, applications of deep … Read more

Katherine Hoadley, PhD

August 9, 2018

We conducted comprehensive integrative molecular analyses of the complete set of tumors in The Cancer Genome Atlas (TCGA), consisting of approximately 10,000 specimens and representing 33 types of cancer. We performed molecular clustering using data on chromosome-arm-level aneuploidy, DNA hypermethylation, mRNA, and miRNA expression levels and reverse-phase protein arrays, of which all, except for aneuploidy, … Read more

Computational Medicine Program

April 16, 2018

Computational Medicine Program Computational Medicine Program to be housed in the newly remodeled Mary Ellen Jones building early 2019.